3eig
From Proteopedia
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[[Image:3eig.png|left|200px]] | [[Image:3eig.png|left|200px]] | ||
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{{STRUCTURE_3eig| PDB=3eig | SCENE= }} | {{STRUCTURE_3eig| PDB=3eig | SCENE= }} | ||
===Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase=== | ===Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019478082</ref><references group="xtra"/> |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 14:41, 27 July 2012
Contents |
Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase
Template:ABSTRACT PUBMED 19478082
About this Structure
3eig is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28. PMID:19478082 doi:10.1074/jbc.M109.018010
