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1p8v

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{{Seed}}
 
[[Image:1p8v.png|left|200px]]
[[Image:1p8v.png|left|200px]]
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{{STRUCTURE_1p8v| PDB=1p8v | SCENE= }}
{{STRUCTURE_1p8v| PDB=1p8v | SCENE= }}
===CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A===
===CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A===
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{{ABSTRACT_PUBMED_12855811}}
{{ABSTRACT_PUBMED_12855811}}
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==Disease==
 
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Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Bernard-Soulier syndrome, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], von Willebrand disease, platelet-type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]]
 
==About this Structure==
==About this Structure==
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1P8V is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8V OCA].
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[[1p8v]] is a 3 chain structure of [[Platelet-receptor glycoprotein Ib alpha]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8V OCA].
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==See Also==
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*[[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha]]
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*[[Thrombin|Thrombin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12855811</ref><references group="xtra"/>
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<ref group="xtra">PMID:012855811</ref><ref group="xtra">PMID:016342940</ref><ref group="xtra">PMID:016673263</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Somers, W S.]]
[[Category: Somers, W S.]]
[[Category: Leucine rich repeat domain]]
[[Category: Leucine rich repeat domain]]
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[[Category: Membrane protein-hydrolase complex]]
[[Category: Platelet glycoprotein receptor]]
[[Category: Platelet glycoprotein receptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:34:34 2009''
 

Revision as of 15:55, 27 July 2012

Image:1p8v.png

Template:STRUCTURE 1p8v

Contents

CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A

Template:ABSTRACT PUBMED 12855811

About this Structure

1p8v is a 3 chain structure of Platelet-receptor glycoprotein Ib alpha and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Dumas JJ, Kumar R, Seehra J, Somers WS, Mosyak L. Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation. Science. 2003 Jul 11;301(5630):222-6. PMID:12855811 doi:http://dx.doi.org/10.1126/science.1083917
  • Wen D, Wildes CP, Silvian L, Walus L, Mi S, Lee DH, Meier W, Pepinsky RB. Disulfide structure of the leucine-rich repeat C-terminal cap and C-terminal stalk region of Nogo-66 receptor. Biochemistry. 2005 Dec 20;44(50):16491-501. PMID:16342940 doi:10.1021/bi0517483
  • Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551

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