1p8v
From Proteopedia
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{{STRUCTURE_1p8v| PDB=1p8v | SCENE= }} | {{STRUCTURE_1p8v| PDB=1p8v | SCENE= }} | ||
===CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A=== | ===CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A=== | ||
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{{ABSTRACT_PUBMED_12855811}} | {{ABSTRACT_PUBMED_12855811}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Bernard-Soulier syndrome, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], von Willebrand disease, platelet-type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1p8v]] is a 3 chain structure of [[Platelet-receptor glycoprotein Ib alpha]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8V OCA]. | |
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| + | ==See Also== | ||
| + | *[[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha]] | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012855811</ref><ref group="xtra">PMID:016342940</ref><ref group="xtra">PMID:016673263</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Somers, W S.]] | [[Category: Somers, W S.]] | ||
[[Category: Leucine rich repeat domain]] | [[Category: Leucine rich repeat domain]] | ||
| + | [[Category: Membrane protein-hydrolase complex]] | ||
[[Category: Platelet glycoprotein receptor]] | [[Category: Platelet glycoprotein receptor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:34:34 2009'' | ||
Revision as of 15:55, 27 July 2012
Contents |
CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A
Template:ABSTRACT PUBMED 12855811
About this Structure
1p8v is a 3 chain structure of Platelet-receptor glycoprotein Ib alpha and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dumas JJ, Kumar R, Seehra J, Somers WS, Mosyak L. Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation. Science. 2003 Jul 11;301(5630):222-6. PMID:12855811 doi:http://dx.doi.org/10.1126/science.1083917
- Wen D, Wildes CP, Silvian L, Walus L, Mi S, Lee DH, Meier W, Pepinsky RB. Disulfide structure of the leucine-rich repeat C-terminal cap and C-terminal stalk region of Nogo-66 receptor. Biochemistry. 2005 Dec 20;44(50):16491-501. PMID:16342940 doi:10.1021/bi0517483
- Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551
