3dg8
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3dg8]] is a 4 chain structure | + | [[3dg8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DG8 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 09:54, 20 October 2012
Contents |
Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP
Template:ABSTRACT PUBMED 19146480
About this Structure
3dg8 is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
See Also
Reference
- Dasgupta T, Chitnumsub P, Kamchonwongpaisan S, Maneeruttanarungroj C, Nichols SE, Lyons TM, Tirado-Rives J, Jorgensen WL, Yuthavong Y, Anderson KS. Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria. ACS Chem Biol. 2009 Jan 16;4(1):29-40. PMID:19146480 doi:10.1021/cb8002804
