3eig

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==About this Structure==
==About this Structure==
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[[3eig]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EIG OCA].
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[[3eig]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EIG OCA].
==See Also==
==See Also==

Revision as of 21:55, 20 October 2012

Template:STRUCTURE 3eig

Contents

Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase

Template:ABSTRACT PUBMED 19478082

About this Structure

3eig is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28. PMID:19478082 doi:10.1074/jbc.M109.018010

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