2voy
From Proteopedia
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{{STRUCTURE_2voy| PDB=2voy | SCENE= }} | {{STRUCTURE_2voy| PDB=2voy | SCENE= }} | ||
| + | ===CryoEM model of CopA, the copper transporting ATPase from Archaeoglobus fulgidus=== | ||
| + | {{ABSTRACT_PUBMED_18547529}} | ||
| - | === | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/COPA_ARCFU COPA_ARCFU]] Probably involved in copper and silver export.<ref>PMID:11756450</ref> [[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). [[http://www.uniprot.org/uniprot/COPA_BACSU COPA_BACSU]] Involved in copper export.<ref>PMID:12644235</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:018547529</ref><references group="xtra"/> | + | <ref group="xtra">PMID:018547529</ref><references group="xtra"/><references/> |
[[Category: Archaeoglobus fulgidus]] | [[Category: Archaeoglobus fulgidus]] | ||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
Revision as of 16:25, 19 June 2013
Contents |
CryoEM model of CopA, the copper transporting ATPase from Archaeoglobus fulgidus
Template:ABSTRACT PUBMED 18547529
Function
[COPA_ARCFU] Probably involved in copper and silver export.[1] [AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). [COPA_BACSU] Involved in copper export.[2]
About this Structure
2voy is a 12 chain structure with sequence from Archaeoglobus fulgidus, Bacillus subtilis and Oryctolagus cuniculus. Full crystallographic information is available from OCA.
Reference
- Wu CC, Rice WJ, Stokes DL. Structure of a copper pump suggests a regulatory role for its metal-binding domain. Structure. 2008 Jun;16(6):976-85. PMID:18547529 doi:http://dx.doi.org/10.1016/j.str.2008.02.025
- ↑ Mandal AK, Cheung WD, Arguello JM. Characterization of a thermophilic P-type Ag+/Cu+-ATPase from the extremophile Archaeoglobus fulgidus. J Biol Chem. 2002 Mar 1;277(9):7201-8. Epub 2001 Dec 26. PMID:11756450 doi:10.1074/jbc.M109964200
- ↑ Radford DS, Kihlken MA, Borrelly GP, Harwood CR, Le Brun NE, Cavet JS. CopZ from Bacillus subtilis interacts in vivo with a copper exporting CPx-type ATPase CopA. FEMS Microbiol Lett. 2003 Mar 14;220(1):105-12. PMID:12644235
