4aas
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:4aas.jpg|left|200px]] | ||
| - | |||
{{STRUCTURE_4aas| PDB=4aas | SCENE= }} | {{STRUCTURE_4aas| PDB=4aas | SCENE= }} | ||
| - | |||
===ATP-triggered molecular mechanics of the chaperonin GroEL=== | ===ATP-triggered molecular mechanics of the chaperonin GroEL=== | ||
| - | |||
{{ABSTRACT_PUBMED_22445172}} | {{ABSTRACT_PUBMED_22445172}} | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] | ||
==About this Structure== | ==About this Structure== | ||
[[4aas]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AAS OCA]. | [[4aas]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AAS OCA]. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Chaperonin|Chaperonin]] | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022445172</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Clare, D K.]] | [[Category: Clare, D K.]] | ||
Revision as of 06:40, 29 September 2013
Contents |
ATP-triggered molecular mechanics of the chaperonin GroEL
Template:ABSTRACT PUBMED 22445172
Function
[CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
About this Structure
4aas is a 14 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR. ATP-triggered conformational changes delineate substrate-binding and -folding mechanics of the GroEL chaperonin. Cell. 2012 Mar 30;149(1):113-23. Epub 2012 Mar 22. PMID:22445172 doi:10.1016/j.cell.2012.02.047
