Sandbox Reserved 806

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 4: Line 4:
<Structure load='2ypi' size='500' frame='true' align='right' caption='Triosephosphate Isomerase' scene='Insert optional scene name here' />
<Structure load='2ypi' size='500' frame='true' align='right' caption='Triosephosphate Isomerase' scene='Insert optional scene name here' />
==Introduction==
==Introduction==
-
This is Triosephosphate isomerase, an enzyme in the glycolytic pathway. It is a dimer, but can function as a <scene name='56/563218/Tim_rotated/1'>monomer</scene>. It catalyzes the reaction of D-glyceraldehyde 3-phosphate to glycerone phosphate.
+
This is Triosephosphate isomerase, an enzyme in the glycolytic pathway. It is a dimer, but can function as a
 +
<scene name='56/563218/Tim_rainbow/1'>monomer</scene>. It catalyzes the reaction of D-glyceraldehyde 3-phosphate to glycerone phosphate. The ligand that binds to it is called 2-Phosphoglycolic acid (PGA).
==3D Structure==
==3D Structure==
Line 19: Line 20:
==Ligand Interaction Site==
==Ligand Interaction Site==
-
The ligand <scene name='56/563218/Interacts_with_substrate/2'>interacts</scene> with the molecule at the location pictured.
+
The ligand--PGA--<scene name='56/563218/Interacts_with_substrate/2'>interacts</scene> with the molecule at the location pictured.
 +
The <scene name='56/563218/Catalytic_residues/1'>catalytic residues</scene> that are 4 Å or less from the ligand, are pictured in green.

Revision as of 18:37, 16 October 2013

This Sandbox is Reserved from Oct 10, 2013, through May 20, 2014 for use in the course "CHEM 410 Biochemistry 1 and 2" taught by Hanna Tims at the Messiah College. This reservation includes Sandbox Reserved 780 through Sandbox Reserved 807.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Triosephosphate Isomerase

Drag the structure with the mouse to rotate

Contents

Introduction

This is Triosephosphate isomerase, an enzyme in the glycolytic pathway. It is a dimer, but can function as a . It catalyzes the reaction of D-glyceraldehyde 3-phosphate to glycerone phosphate. The ligand that binds to it is called 2-Phosphoglycolic acid (PGA).

3D Structure

The contains alpha helices (gold) and beta sheets (purple). Overall, it forms a beta barrel motif.

was not working.

Residues

Pictured in yellow are the . The are pictured in green.

Solvent Accessibility

are pictured in dark blue. They are mostly located between the beta sheets and alpha helices, in a diagonal line, closer to where the monomers connect to form a dimer.

Ligand Interaction Site

The ligand--PGA-- with the molecule at the location pictured. The that are 4 Å or less from the ligand, are pictured in green.

Retrieved from "http://52.214.119.220/wiki/index.php/Sandbox_Reserved_806"
Personal tools