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4h95

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==About this Structure==
==About this Structure==
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[[4h95]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H95 OCA].
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[[4h95]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H95 OCA].
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[[Category: Candida albicans]]
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==See Also==
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
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==Reference==
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<ref group="xtra">PMID:023375226</ref><references group="xtra"/><references/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Anderson, A C.]]
[[Category: Anderson, A C.]]

Revision as of 12:13, 20 November 2013

Template:STRUCTURE 4h95

Contents

Candida albicans dihydrofolate reductase complexed with NADPH and 6-ethyl-5-{3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine (UCP1006)

Template:ABSTRACT PUBMED 23375226

About this Structure

4h95 is a 2 chain structure with sequence from candida_stellatoidea Atcc 11006 candida stellatoidea. Full crystallographic information is available from OCA.

See Also

Reference

  • Paulsen JL, Viswanathan K, Wright DL, Anderson AC. Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1279-84. doi: 10.1016/j.bmcl.2013.01.008. , Epub 2013 Jan 11. PMID:23375226 doi:http://dx.doi.org/10.1016/j.bmcl.2013.01.008

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