3f0q

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[[Image:3f0q.png|left|200px]]
 
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{{STRUCTURE_3f0q| PDB=3f0q | SCENE= }}
{{STRUCTURE_3f0q| PDB=3f0q | SCENE= }}
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===Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine===
===Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine===
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{{ABSTRACT_PUBMED_20643959}}
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{{ABSTRACT_PUBMED_20643959}}
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==Function==
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[[http://www.uniprot.org/uniprot/Q2YY41_STAAB Q2YY41_STAAB]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
==About this Structure==
==About this Structure==
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[[3f0q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F0Q OCA].
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[[3f0q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staab Staab]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F0Q OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:020643959</ref><references group="xtra"/>
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<ref group="xtra">PMID:020643959</ref><references group="xtra"/><references/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: Staphylococcus aureus rf122]]
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[[Category: Staab]]
[[Category: Anderson, A C.]]
[[Category: Anderson, A C.]]
[[Category: Frey, K M.]]
[[Category: Frey, K M.]]

Revision as of 08:39, 27 November 2013

Template:STRUCTURE 3f0q

Contents

Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine

Template:ABSTRACT PUBMED 20643959

Function

[Q2YY41_STAAB] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

About this Structure

3f0q is a 1 chain structure with sequence from Staab. Full crystallographic information is available from OCA.

See Also

Reference

  • Frey KM, Georgiev I, Donald BR, Anderson AC. Predicting resistance mutations using protein design algorithms. Proc Natl Acad Sci U S A. 2010 Jul 19. PMID:20643959

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