Interferon receptor (IFNR) is a cell surface receptor which binds interferon. Interferon α/β receptor binds interferon-α and interferon-β. It is a heterodimer with subunits INFAR1 and INFAR2. Interferon γ receptor binds interferon-γ and is a heterodimer with subunits INFGR1 and INFGR2. Interferon δ receptor binds interferon-δ.
3D structures of interferon receptor
Updated on 19-March-2014
Interferon α/β receptor
3s98 – hINFAR1 ectodomain – human
1n6u, 1n6v – hINFAR2 ectodomain - NMR
3s8w – hINFAR2 D2 domain - NMR
2hym, 2kz1, 2lag – hINFAR2 ectodomain + interferon-α 2 - NMR
3s9d – hINFAR2 ectodomain + interferon-α 2
3se3 – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-α 2
3se4 – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-ω 1
3wcy – INFAR1 ectodomain + interferon-β - mouse
Interferon γ receptor
1jrh – hINFGR1 N terminal (mutant) + antibody
1fg9, 1fyh – hINFGR1 extracellular domain + interferon-γ
4eq2, 4eq3 – INFGR1 α chain - chicken
Interferon δ receptor
3og4, 3og6 – hINFDR1 extracellular domain + interleukin-29
