User:Gisselle Medina/Sandbox7 Leader
From Proteopedia
(Difference between revisions)
(→Structure) |
(→Structure) |
||
| Line 4: | Line 4: | ||
==Structure== | ==Structure== | ||
<Structure load='2JQG' size='400' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='2JQG' size='400' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
| - | The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and | + | The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> CTE is composed of 18 amino acid residues and presumably can fold back into its own active site. <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene> |
| - | CTE is composed of 18 amino acid residues and presumably can fold back into its own active site. <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene> | + | |
Revision as of 14:54, 16 May 2014
Introduction
Structure
|
The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible CTE is composed of 18 amino acid residues and presumably can fold back into its own active site.
