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User:Gisselle Medina/Sandbox7 Leader
From Proteopedia
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<Structure load='2JQG' size='400' frame='true' align='right' caption='Insert caption here' scene='FMDV Lpro' /> | <Structure load='2JQG' size='400' frame='true' align='right' caption='Insert caption here' scene='FMDV Lpro' /> | ||
The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> CTE is composed of 18 amino acid residues and presumably can fold back into its own <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene>. | The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> CTE is composed of 18 amino acid residues and presumably can fold back into its own <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene>. | ||
| - | an | + | an <scene name='48/484916/Alpha_helix/1'>α-helical</scene> domain on the left and a predominantly β-sheet domain on the right |
Revision as of 11:56, 17 May 2014
Introduction
Structure
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The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible CTE is composed of 18 amino acid residues and presumably can fold back into its own . an domain on the left and a predominantly β-sheet domain on the right
