User:Gisselle Medina/Sandbox7 Leader

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==Structure==
==Structure==
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<Structure load='2JQG' size='450' frame='true' align='right' caption='FMDV Lbpro' scene='Insert optional scene name here'>__NOTOC__
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<Structure load='2JQG' size='450' frame='true' align='right' caption='FMDV Lbpro'scene='48/484916/Starting_molecule/3'>TextToBeDisplayed</scene'>
The <scene name='48/484916/Starting_molecule/1'>leader protein</scene> from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> CTE is composed of 18 amino acid residues and presumably can fold back into its own <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene>.
The <scene name='48/484916/Starting_molecule/1'>leader protein</scene> from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and upon translation frees itself by self cleavage.This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> CTE is composed of 18 amino acid residues and presumably can fold back into its own <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene>.
Lbpro contains an <scene name='48/484916/Alpha_helix/1'>α-helical</scene> domain on the left and a predominantly <scene name='48/484916/Beta_sheet/1'>β-sheet</scene> domain on the right.
Lbpro contains an <scene name='48/484916/Alpha_helix/1'>α-helical</scene> domain on the left and a predominantly <scene name='48/484916/Beta_sheet/1'>β-sheet</scene> domain on the right.

Revision as of 19:20, 17 May 2014

Introduction

Structure

PDB ID 2JQG

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Gisselle Medina

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