1bso

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[[Image:1bso.gif|left|200px]]<br /><applet load="1bso" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1bso.gif|left|200px]]
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caption="1bso, resolution 2.23&Aring;" />
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'''12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN'''<br />
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{{Structure
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|PDB= 1bso |SIZE=350|CAPTION= <scene name='initialview01'>1bso</scene>, resolution 2.23&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=BRC:12-BROMODODECANOIC ACID'>BRC</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1BSO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=BRC:'>BRC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSO OCA].
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1BSO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSO OCA].
==Reference==
==Reference==
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12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin., Qin BY, Creamer LK, Baker EN, Jameson GB, FEBS Lett. 1998 Nov 6;438(3):272-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9827560 9827560]
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12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin., Qin BY, Creamer LK, Baker EN, Jameson GB, FEBS Lett. 1998 Nov 6;438(3):272-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9827560 9827560]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: x-ray crystal structure]]
[[Category: x-ray crystal structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:58:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:15:15 2008''

Revision as of 08:15, 20 March 2008

Image:1bso.gif


PDB ID 1bso

Drag the structure with the mouse to rotate
, resolution 2.23Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN


Overview

The X-ray structure of bovine beta-lactoglobulin with the ligand 12-bromododecanoic acid as a model for fatty acids has been determined at a resolution of 2.23 A in the trigonal lattice Z form. The ligand binds inside the calyx, resolving a long-standing controversy as to where fatty-acid like ligands bind. The carboxylate head group lies at the surface of the molecule, and the lid to the calyx is open at the pH of crystallization (pH 7.3), consistent with the conformation observed in ligand-free bovine beta-lactoglobulin in lattice Z at pH 7.1 and pH 8.2.

About this Structure

1BSO is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin., Qin BY, Creamer LK, Baker EN, Jameson GB, FEBS Lett. 1998 Nov 6;438(3):272-8. PMID:9827560

Page seeded by OCA on Thu Mar 20 10:15:15 2008

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