2ymw

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{{STRUCTURE_2ymw| PDB=2ymw | SCENE= }}
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==Structure of the epsilon-lysine oxidase from Marinomonas mediterranea==
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===Structure of the epsilon-lysine oxidase from Marinomonas mediterranea===
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<StructureSection load='2ymw' size='340' side='right' caption='[[2ymw]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[2ymw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Marinomonas_mediterranea_mmb-1 Marinomonas mediterranea mmb-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YMW FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/LODA_MARM1 LODA_MARM1]] Has antibacterial activity against a wide spectrum of Gram-positive and Gram-negative bacteria including nosocomial isolates of S.aureus and Pseudomonas sp. The antimicrobial activity is due to hydrogen peroxide generated by its lysine oxidase activity. Also has autotoxic activity. Involved in biofilm differentiation; responsible for cell death within microcolonies during biofilm development which is linked to the generation of a phenotypically diverse dispersal population and thus may play a role in colonization.<ref>PMID:15652194</ref> <ref>PMID:18502869</ref> <ref>PMID:20025674</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lysine_6-oxidase L-lysine 6-oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.20 1.4.3.20] </span></td></tr>
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[[2ymw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Marinomonas_mediterranea_mmb-1 Marinomonas mediterranea mmb-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YMW OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ymw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ymw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ymw RCSB], [http://www.ebi.ac.uk/pdbsum/2ymw PDBsum]</span></td></tr>
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</table>
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==Reference==
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__TOC__
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<references group="xtra"/><references/>
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</StructureSection>
[[Category: L-lysine 6-oxidase]]
[[Category: L-lysine 6-oxidase]]
[[Category: Marinomonas mediterranea mmb-1]]
[[Category: Marinomonas mediterranea mmb-1]]
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[[Category: Medrano, F J.]]
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[[Category: Medrano, F J]]
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[[Category: Romero, A.]]
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[[Category: Romero, A]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 14:05, 18 December 2014

Structure of the epsilon-lysine oxidase from Marinomonas mediterranea

2ymw, resolution 2.41Å

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