3u3r
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u3r RCSB], [http://www.ebi.ac.uk/pdbsum/3u3r PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u3r RCSB], [http://www.ebi.ac.uk/pdbsum/3u3r PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ST1A1_HUMAN ST1A1_HUMAN]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.<ref>PMID:12471039</ref> <ref>PMID:16221673</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 21:59, 24 December 2014
Crystal structure of D249G mutated Human SULT1A1 bound to PAP and P-NITROPHENOL
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