3jw5

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jw5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jw5 RCSB], [http://www.ebi.ac.uk/pdbsum/3jw5 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jw5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jw5 RCSB], [http://www.ebi.ac.uk/pdbsum/3jw5 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q81R22_BACAN Q81R22_BACAN]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 22:32, 24 December 2014

Crystal structure of Bacillus anthracis (Y102F) dihydrofolate reductase complexed with NADPH and Trimethoprim

3jw5, resolution 2.89Å

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