1kcf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1kcf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KCF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1kcf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KCF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPAC25G10.02 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 Schizosaccharomyces pombe])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPAC25G10.02 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 Schizosaccharomyces pombe])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kcf RCSB], [http://www.ebi.ac.uk/pdbsum/1kcf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kcf RCSB], [http://www.ebi.ac.uk/pdbsum/1kcf PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CCE1_SCHPO CCE1_SCHPO]] Capable of resolving Holliday junctions. Specific for 4-way junctions. Seems to be important for the maintenance of mitochondrial DNA. Cleaves fixed junctions at the point of strand exchange. Cleaves after 5'-CT-3' and 5'-TT-3' sequences.<ref>PMID:9343409</ref> <ref>PMID:10954073</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Barrett, T E.]]
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[[Category: Barrett, T E]]
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[[Category: Ceschini, S.]]
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[[Category: Ceschini, S]]
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[[Category: Keeley, A.]]
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[[Category: Keeley, A]]
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[[Category: McAlister, M S.B.]]
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[[Category: McAlister, M S.B]]
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[[Category: Oram, M.]]
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[[Category: Oram, M]]
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[[Category: Pearl, L H.]]
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[[Category: Pearl, L H]]
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[[Category: Phelan, J.]]
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[[Category: Phelan, J]]
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[[Category: Tsaneva, I R.]]
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[[Category: Tsaneva, I R]]
[[Category: Beta-alpha-beta motif]]
[[Category: Beta-alpha-beta motif]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Ruvc resolvase family]]
[[Category: Ruvc resolvase family]]

Revision as of 23:52, 24 December 2014

Crystal Structure of the Yeast Mitochondrial Holliday Junction Resolvase, Ydc2

1kcf, resolution 2.30Å

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