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3v69
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3v69]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V69 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V69 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3v69]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V69 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V69 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BL6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BL6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v69 RCSB], [http://www.ebi.ac.uk/pdbsum/3v69 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v69 RCSB], [http://www.ebi.ac.uk/pdbsum/3v69 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FILIA_MOUSE FILIA_MOUSE]] Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function. Capable of binding RNA.<ref>PMID:19376971</ref> <ref>PMID:22276159</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA.,Wang J, Xu M, Zhu K, Li L, Liu X PLoS One. 2012;7(1):e30209. Epub 2012 Jan 19. PMID:22276159<ref>PMID:22276159</ref> | The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA.,Wang J, Xu M, Zhu K, Li L, Liu X PLoS One. 2012;7(1):e30209. Epub 2012 Jan 19. PMID:22276159<ref>PMID:22276159</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Li, L | + | [[Category: Li, L]] |
| - | [[Category: Liu, X | + | [[Category: Liu, X]] |
| - | [[Category: Wang, J | + | [[Category: Wang, J]] |
| - | [[Category: Xu, M | + | [[Category: Xu, M]] |
| - | [[Category: Zhu, K | + | [[Category: Zhu, K]] |
[[Category: Embryogenesis]] | [[Category: Embryogenesis]] | ||
[[Category: Filia]] | [[Category: Filia]] | ||
Revision as of 01:37, 25 December 2014
Filia-N crystal structure
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Categories: Mus musculus | Li, L | Liu, X | Wang, J | Xu, M | Zhu, K | Embryogenesis | Filia | Kh domain | Protein binding | Rna binding | Rna-binding
