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3ubb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ubb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UBB FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ubb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UBB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3UB:PROPAN-2-YL+HYDROGEN+(S)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}ETHYL]PHOSPHONATE'>3UB</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3UB:PROPAN-2-YL+HYDROGEN+(S)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}ETHYL]PHOSPHONATE'>3UB</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpG, b3424, JW5687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpG, b3424, JW5687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ubb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ubb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ubb RCSB], [http://www.ebi.ac.uk/pdbsum/3ubb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ubb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ubb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ubb RCSB], [http://www.ebi.ac.uk/pdbsum/3ubb PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.,Xue Y, Chowdhury S, Liu X, Akiyama Y, Ellman J, Ha Y Biochemistry. 2012 May 8;51(18):3723-31. Epub 2012 Apr 24. PMID:22515733<ref>PMID:22515733</ref> | Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.,Xue Y, Chowdhury S, Liu X, Akiyama Y, Ellman J, Ha Y Biochemistry. 2012 May 8;51(18):3723-31. Epub 2012 Apr 24. PMID:22515733<ref>PMID:22515733</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Rhomboid protease]] | [[Category: Rhomboid protease]] | ||
| - | [[Category: Ha, Y | + | [[Category: Ha, Y]] |
| - | [[Category: Xue, Y | + | [[Category: Xue, Y]] |
[[Category: Helix bundle]] | [[Category: Helix bundle]] | ||
[[Category: Hydrolase-inhibitor complex]] | [[Category: Hydrolase-inhibitor complex]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
Revision as of 04:02, 25 December 2014
The crystal structure of GlpG in complex with a phosphonofluoridate inhibitor
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