1z1g

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z1g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. The December 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Transposase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_12 10.2210/rcsb_pdb/mom_2006_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1G FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z1g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. The December 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Transposase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_12 10.2210/rcsb_pdb/mom_2006_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1G FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p7d|1p7d]], [[1z19|1z19]], [[1z1b|1z1b]], [[1kjk|1kjk]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p7d|1p7d]], [[1z19|1z19]], [[1z1b|1z1b]], [[1kjk|1kjk]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">INT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Enterobacteria phage lambda])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">INT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Enterobacteria phage lambda])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1g RCSB], [http://www.ebi.ac.uk/pdbsum/1z1g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1g RCSB], [http://www.ebi.ac.uk/pdbsum/1z1g PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD]] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Transposase]]
[[Category: Transposase]]
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[[Category: Aihara, H.]]
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[[Category: Aihara, H]]
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[[Category: Biswas, T.]]
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[[Category: Biswas, T]]
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[[Category: Ellenberger, T.]]
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[[Category: Ellenberger, T]]
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[[Category: Filman, D.]]
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[[Category: Filman, D]]
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[[Category: Landy, A.]]
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[[Category: Landy, A]]
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[[Category: Radman-Livaja, M.]]
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[[Category: Radman-Livaja, M]]
[[Category: Dna binding protein-dna complex]]
[[Category: Dna binding protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]

Revision as of 06:35, 25 December 2014

Crystal structure of a lambda integrase tetramer bound to a Holliday junction

1z1g, resolution 4.40Å

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