1q8r
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1q8r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q8R FirstGlance]. <br> | <table><tr><td colspan='2'>[[1q8r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q8R FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rusa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rusa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1q8r RCSB], [http://www.ebi.ac.uk/pdbsum/1q8r PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1q8r RCSB], [http://www.ebi.ac.uk/pdbsum/1q8r PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RUSA_ECOLI RUSA_ECOLI]] Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 32: | Line 34: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Baker, P J | + | [[Category: Baker, P J]] |
| - | [[Category: Bolt, E L | + | [[Category: Bolt, E L]] |
| - | [[Category: Leonard, P | + | [[Category: Leonard, P]] |
| - | [[Category: Lloyd, R G | + | [[Category: Lloyd, R G]] |
| - | [[Category: Muranova, T A | + | [[Category: Muranova, T A]] |
| - | [[Category: Pasquo, A | + | [[Category: Pasquo, A]] |
| - | [[Category: Rafferty, J B | + | [[Category: Rafferty, J B]] |
| - | [[Category: Rice, D W | + | [[Category: Rice, D W]] |
| - | [[Category: Sedelnikova, S E | + | [[Category: Sedelnikova, S E]] |
| - | [[Category: Sharples, G J | + | [[Category: Sharples, G J]] |
[[Category: Chorismate mutase-like fold]] | [[Category: Chorismate mutase-like fold]] | ||
[[Category: Extended mixed beta sheet]] | [[Category: Extended mixed beta sheet]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Recombination]] | [[Category: Recombination]] | ||
Revision as of 12:51, 25 December 2014
Structure of E.coli RusA Holliday junction resolvase
| |||||||||||
