3u3m
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u3m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u3m RCSB], [http://www.ebi.ac.uk/pdbsum/3u3m PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u3m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u3m RCSB], [http://www.ebi.ac.uk/pdbsum/3u3m PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ST1A1_HUMAN ST1A1_HUMAN]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.<ref>PMID:12471039</ref> <ref>PMID:16221673</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 14:58, 25 December 2014
Crystal structure of Human SULT1A1 bound to PAP and 3-Cyano-7-hydroxycoumarin
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