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3jvx

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jvx RCSB], [http://www.ebi.ac.uk/pdbsum/3jvx PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jvx RCSB], [http://www.ebi.ac.uk/pdbsum/3jvx PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q81R22_BACAN Q81R22_BACAN]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 18:49, 25 December 2014

Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120A)

3jvx, resolution 2.25Å

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