4ee9
From Proteopedia
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| - | + | ==Crystal structure of the RBcel1 endo-1,4-glucanase== | |
| - | === | + | <StructureSection load='4ee9' size='340' side='right' caption='[[4ee9]], [[Resolution|resolution]] 1.38Å' scene=''> |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4ee9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Uncultured_bacterium Uncultured bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EE9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ee9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ee9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ee9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ee9 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | RBcel1 is an endoglucanase belonging to glycoside hydrolase family 5 subfamily 5 (GH5_5) that was recently identified from a soil metagenome library from the Antarctic. Unlike its closest structural homologue (Cel5A from Thermoascus aurantiacus), this enzyme was reported to be able to catalyze transglycosylation reactions and has putatively been implicated in the bacterial cellulose-synthesis process. Here, the structure of RBcel1 at 1.4 A resolution, solved by molecular replacement, is reported. The structure and putative substrate-binding site are described and compared with those of other GH5_5 subfamily members. | ||
| - | + | Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase.,Delsaute M, Berlemont R, Dehareng D, Van Elder D, Galleni M, Bauvois C Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):828-33. doi: , 10.1107/S1744309113014565. Epub 2013 Jul 26. PMID:23908022<ref>PMID:23908022</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | |||
| + | ==See Also== | ||
| + | *[[Glucanase|Glucanase]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Cellulase]] | [[Category: Cellulase]] | ||
[[Category: Uncultured bacterium]] | [[Category: Uncultured bacterium]] | ||
| - | [[Category: Bauvois, C | + | [[Category: Bauvois, C]] |
| - | [[Category: Berlemont, R | + | [[Category: Berlemont, R]] |
| - | [[Category: Delsaute, M | + | [[Category: Delsaute, M]] |
| - | [[Category: Elder, D Van | + | [[Category: Elder, D Van]] |
| - | [[Category: Galleni, M | + | [[Category: Galleni, M]] |
[[Category: 4-endoglucanase]] | [[Category: 4-endoglucanase]] | ||
[[Category: Beta-1]] | [[Category: Beta-1]] | ||
| - | [[Category: Cellulase]] | ||
[[Category: Glycosyl hydrolase family 5]] | [[Category: Glycosyl hydrolase family 5]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Tim barrel]] | [[Category: Tim barrel]] | ||
Revision as of 12:53, 5 January 2015
Crystal structure of the RBcel1 endo-1,4-glucanase
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