Magainin 2
From Proteopedia
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AMPs consists of 10-50 amino acids, and are produced by Eukaryotes, as part of their defence mechanism from bacteria. For informatoin about AMP you can visit the Proteopedia page [[Antimicrobial peptides]] | AMPs consists of 10-50 amino acids, and are produced by Eukaryotes, as part of their defence mechanism from bacteria. For informatoin about AMP you can visit the Proteopedia page [[Antimicrobial peptides]] | ||
They were discovered by Dr. Michael Zasloff and first reported in 1987. | They were discovered by Dr. Michael Zasloff and first reported in 1987. | ||
- | == Function == | ||
- | == | + | ==Magainin and Magainin 2== |
+ | Magainin and Magainin 2 were discovered together, and posses very similar sequences, of 20 Amino Acid long. | ||
+ | |||
+ | Magainin: Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-<span style='background-color: yellow;'>Lys</span>-Ser | ||
+ | magainin 2: Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-<span style='background-color: yellow;'>Asn</span>-Ser | ||
+ | |||
- | == Relevance == | ||
== Structural highlights == | == Structural highlights == |
Revision as of 08:15, 23 January 2015
Magainin 2
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644