4u5m

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u5m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u5m RCSB], [http://www.ebi.ac.uk/pdbsum/4u5m PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u5m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u5m RCSB], [http://www.ebi.ac.uk/pdbsum/4u5m PDBsum]</span></td></tr>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Aside from the well-known double helix, DNA can also adopt an alternative four-stranded structure known as G-quadruplex. Implications of such a structure in cellular processes, as well as its therapeutic and diagnostic applications, have been reported. The G-quadruplex structure is highly polymorphic, but so far, only right-handed helical forms have been observed. Here we present the NMR solution and X-ray crystal structures of a left-handed DNA G-quadruplex. The structure displays unprecedented features that can be exploited as unique recognition elements.
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Structure of a left-handed DNA G-quadruplex.,Chung WJ, Heddi B, Schmitt E, Lim KW, Mechulam Y, Phan AT Proc Natl Acad Sci U S A. 2015 Feb 18. pii: 201418718. PMID:25695967<ref>PMID:25695967</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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Revision as of 11:24, 4 March 2015

Structure of a left-handed DNA G-quadruplex

4u5m, resolution 1.50Å

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