Serine/threonine protein kinase

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Line 36: Line 36:
**[[1nvs]], [[1zys]] - hChk1 kinase domain + peptide + inhibitor
**[[1nvs]], [[1zys]] - hChk1 kinase domain + peptide + inhibitor
-
**[[2cgu]], [[2cgv]], [[2cgw]], [[2cgx]], [[2c3j]], [[2c3k]], [[2c3l]], [[2br1]], [[2brb]], [[2brg]], [[2brh]], [[2brm]], [[2brn]], [[2bro]], [[2ayp]], [[2gdo]], [[2ghg]], [[2hog]], [[2ywp]], [[2hxl]], [[2hxq]], [[2hy0]], [[2r0u]], [[2e9n]], [[2e9o]], [[2e9p]], [[2e9u]], [[2e9v]], [[2qhm]], [[2qhn]], [[3f9n]], [[2wmq]], [[2wmr]], [[2wms]], [[2wmt]], [[2wmu]], [[2wmv]], [[2wmx]], [[3jvr]], [[3jvs]], [[2xey]], [[2xf0]], [[2xez]], [[2x8d]], [[2x8e]], [[2x8i]], [[3ot3]], [[3ot8]], [[3pa3]], [[3pa4]], [[3pa5]], [[3nlb]], [[2wmw]], [[2ydi]], [[2ydj]], [[2ydk]], [[2yer]], [[2yex]], [[2ym3]], [[2ym4]], [[2ym5]], [[2ym6]], [[2ym7]], [[2ym8]], [[3tkh]], [[3tki]], [[3u9n]], [[4fsm]], [[4fsn]], [[4fsq]], [[4fsr]], [[4fst]], [[4fsu]], [[4fsw]], [[4fsy]], [[4fsz]], [[4ft0]], [[4ft3]], [[4ft5]], [[4ft7]], [[4ft9]], [[4fta]], [[4ftc]], [[4fti]], [[4ftj]], [[4ftk]], [[4ftl]], [[4ftm]], [[4ftn]], [[4fto]], [[4ftq]], [[4ftr]], [[4ftt]], [[4ftu]], [[4gh2]], [[4hyh]], [[4hyi]], [[4jik]] - hChk1 kinase domain + inhibitor<br />
+
**[[2cgu]], [[2cgv]], [[2cgw]], [[2cgx]], [[2c3j]], [[2c3k]], [[2c3l]], [[2br1]], [[2brb]], [[2brg]], [[2brh]], [[2brm]], [[2brn]], [[2bro]], [[2ayp]], [[2gdo]], [[2ghg]], [[2hog]], [[2ywp]], [[2hxl]], [[2hxq]], [[2hy0]], [[2r0u]], [[2e9n]], [[2e9o]], [[2e9p]], [[2e9u]], [[2e9v]], [[2qhm]], [[2qhn]], [[3f9n]], [[2wmq]], [[2wmr]], [[2wms]], [[2wmt]], [[2wmu]], [[2wmv]], [[2wmx]], [[3jvr]], [[3jvs]], [[2xey]], [[2xf0]], [[2xez]], [[2x8d]], [[2x8e]], [[2x8i]], [[3ot3]], [[3ot8]], [[3pa3]], [[3pa4]], [[3pa5]], [[3nlb]], [[2wmw]], [[2ydi]], [[2ydj]], [[2ydk]], [[2yer]], [[2yex]], [[2ym3]], [[2ym4]], [[2ym5]], [[2ym6]], [[2ym7]], [[2ym8]], [[3tkh]], [[3tki]], [[3u9n]], [[4fsm]], [[4fsn]], [[4fsq]], [[4fsr]], [[4fst]], [[4fsu]], [[4fsw]], [[4fsy]], [[4fsz]], [[4ft0]], [[4ft3]], [[4ft5]], [[4ft7]], [[4ft9]], [[4fta]], [[4ftc]], [[4fti]], [[4ftj]], [[4ftk]], [[4ftl]], [[4ftm]], [[4ftn]], [[4fto]], [[4ftq]], [[4ftr]], [[4ftt]], [[4ftu]], [[4gh2]], [[4hyh]], [[4hyi]], [[4jik]], [[4rvm]], [[4rvl]], [[4rvk]], [[4qyh]], [[4qyg]], [[4qyf]], [[4qye]] - hChk1 kinase domain + inhibitor<br />
**[[2jqi]] – yChk1 – yeast<br />
**[[2jqi]] – yChk1 – yeast<br />
Line 47: Line 47:
**[[2cn8]] – hChk2 kinase domain + inhibitor
**[[2cn8]] – hChk2 kinase domain + inhibitor
-
**[[2w0j]], [[2w7x]], [[2wtc]], [[2wtd]], [[2xbj]], [[2xm8]], [[2xm9]], [[2yiq]], [[2yir]], [[2yit]], [[2cn8]], [[2ycf]], [[2ycq]], [[2ycr]], [[2ycs]], [[2wti]], [[2wtj]], [[2xk9]], [[4a9r]], [[4a9s]], [[4a9t]], [[4bda]], [[4bdb]], [[4bdc]], [[4bdd]], [[4bde]], [[4bdf]], [[4bdg]], [[4bdh]], [[4bdi]], [[4bdj]], [[4bdk]] - hChk2 kinase domain + inhibitor
+
**[[2w0j]], [[2w7x]], [[2wtc]], [[2wtd]], [[2xbj]], [[2xm8]], [[2xm9]], [[2yiq]], [[2yir]], [[2yit]], [[2cn8]], [[2ycf]], [[2ycq]], [[2ycr]], [[2ycs]], [[2wti]], [[2wtj]], [[2xk9]], [[4a9r]], [[4a9s]], [[4a9t]], [[4bda]], [[4bdb]], [[4bdc]], [[4bdd]], [[4bde]], [[4bdf]], [[4bdg]], [[4bdh]], [[4bdi]], [[4bdj]], [[4bdk]], [[2uv2]] - hChk2 kinase domain + inhibitor
**[[3i6u]], [[3i6w]] – hChk2 residues 84-502 (mutant)
**[[3i6u]], [[3i6w]] – hChk2 residues 84-502 (mutant)
Line 53: Line 53:
*'''Chk3 (Mst2)'''
*'''Chk3 (Mst2)'''
-
**[[4hkd]], [[4l0n]] – hChk3 SARAH domain<br />
+
**[[4hkd]], [[4l0n]], [[4oh9]] – hChk3 SARAH domain<br />
**[[4lg4]] – hChk3 kinase domain<br />
**[[4lg4]] – hChk3 kinase domain<br />
**[[4lgd]] – hChk3 kinase domain + RASSF5 SARAH domain<br />
**[[4lgd]] – hChk3 kinase domain + RASSF5 SARAH domain<br />
Line 62: Line 62:
**[[3com]] – hChk4 kinase domain<br />
**[[3com]] – hChk4 kinase domain<br />
**[[4nr2]] – hChk4 SARAH domain<br />
**[[4nr2]] – hChk4 SARAH domain<br />
 +
**[[4oh8]] – hChk4 SARAH domain + Ras association domain-containing protein<br />
*'''Chk5 (Aurora kinase b)'''
*'''Chk5 (Aurora kinase b)'''
Line 87: Line 88:
*'''Chk10'''
*'''Chk10'''
-
**[[2j7t]], [[4aot]], [[4equ]] – hChk10 kinase domain + inhibitor<br />
+
**[[2j7t]], [[4aot]], [[4equ]], [[5ajq]] – hChk10 kinase domain + inhibitor<br />
*'''Chk11'''
*'''Chk11'''
Line 107: Line 108:
*Plk1 Pbd complex with polypeptide
*Plk1 Pbd complex with polypeptide
-
**[[1umw]], [[2ojx]], [[3bzi]], [[3c5l]], [[3rq7]], [[4dfw]] – Plk1 Pbd + peptide<br />
+
**[[1umw]], [[2ojx]], [[3bzi]], [[3c5l]], [[3rq7]], [[4dfw]], [[4whl]], [[4whk]], [[4whh]], [[4rcp]], [[4o6w]], [[4o56]] – Plk1 Pbd + peptide<br />
-
**[[3hik]], [[3fvh]], [[3p2z]], [[3p34]], [[3p35]], [[3p36]], [[3p37]], [[3q1i]], [[4e67]], [[4e9c]], [[4e9d]], [[4hab]], [[4hy2]] – Plk1 Pbd + phosphopeptide<br />
+
**[[3hik]], [[3fvh]], [[3p2z]], [[3p34]], [[3p35]], [[3p36]], [[3p37]], [[3q1i]], [[4e67]], [[4e9c]], [[4e9d]], [[4hab]], [[4hy2]], [[4o9w]] – Plk1 Pbd + phosphopeptide<br />
**[[1q4k]] – Plk1 Pbd (mutant) + phosphopeptide<br />
**[[1q4k]] – Plk1 Pbd (mutant) + phosphopeptide<br />
**[[2v5q]] – Plk1 Pbd + design ankyrin repeat protein<br />
**[[2v5q]] – Plk1 Pbd + design ankyrin repeat protein<br />
Line 133: Line 134:
*'''Plk2'''
*'''Plk2'''
-
**[[4i5m]], [[4i5p]], [[4i6f]], [[4i6h]] – hChk Plk2 (mutant) + inhibitor <br />
+
**[[4i5m]], [[4i5p]], [[4i6f]], [[4i6h]] – hChk Plk2 kinase domain (mutant) + inhibitor <br />
 +
**[[4xb0]], [[4rs6]] – hChk Plk2 Pbd <br />
*'''Plk3'''
*'''Plk3'''
**[[4b6l]], [[4i6b]] – hChk Plk3 kinase domain + inhibitor<br />
**[[4b6l]], [[4i6b]] – hChk Plk3 kinase domain + inhibitor<br />
 +
 +
*'''Plk4'''
 +
 +
**[[3cok]] – hChk Plk4 kinase domain<br />
 +
**[[4n9j]] – hChk Plk4 Pbd domain<br />
 +
**[[4n7z]], [[4n7v]] – hChk Plk4 Pbd domain + centrosomal protein <br />
 +
**[[4jxf]] – hChk Plk4 + inhibitor<br />
 +
**[[4nk7]], [[4g7n]] – Chk Plk4 Pbd domain – ''Drosophila melanogaster''<br />
*'''Chk15 (Aurora kinase a)'''
*'''Chk15 (Aurora kinase a)'''
-
**[[4bn1]] – hChk15 (mutant) <br />
+
**[[4o0s]] – hChk15 kinase domain <br />
-
**[[4byi]], [[4byj]], [[4jai]], [[4jaj]], [[3w10]], [[3w16]], [[3w18]], [[3w2c]] – hChk15 kinase domain + inhibitor <br />
+
**[[4bn1]], [[4o0w]], [[4o0u]] – hChk15 kinase domain (mutant) <br />
-
**[[4jbo]], [[4jbp]], [[4jbq]] – hChk15 kinase domain (mutant) + inhibitor <br />
+
**[[4byi]], [[4byj]], [[4jai]], [[4jaj]], [[3w10]], [[3w16]], [[3w18]], [[3w2c]], [[4uzh]], [[4uzd]], [[4uyn]] – hChk15 kinase domain + inhibitor <br />
 +
**[[4jbo]], [[4jbp]], [[4jbq]], [[4prj]] – hChk15 kinase domain (mutant) + inhibitor <br />
*'''Chk16'''
*'''Chk16'''
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**[[3lm5]] – hChk17B + quercetin<br />
**[[3lm5]] – hChk17B + quercetin<br />
-
*'''Chk24'''
+
*'''Chk24 (Mst3)'''
**[[3a7f]], [[3a7g]], [[3a7h]], [[3a7i]], [[3a7j]], [[3ckw]] – hChk24 kinase domain <br />
**[[3a7f]], [[3a7g]], [[3a7h]], [[3a7i]], [[3a7j]], [[3ckw]] – hChk24 kinase domain <br />
 +
**[[4w8e]], [[4w8d]], [[4u8z]] – hChk Mst3 + inhibitor <br />
**[[3ckx]] – hChk24 kinase domain + staurosporin <br />
**[[3ckx]] – hChk24 kinase domain + staurosporin <br />
**[[3zhp]] – hChk24 kinase domain + calcium-binding protein <br />
**[[3zhp]] – hChk24 kinase domain + calcium-binding protein <br />
 +
**[[4o27]] – hChk24 kinase domain (mutant) + calcium-binding protein <br />
 +
 +
*'''Chk26 (Mst4)'''
 +
 +
**[[3ggf]] – hChk Mst4 + inhibitor <br />
 +
**[[4geh]], [[3w8i]] - hChk Mst4 dimerization domain + programmed cell death protein 10<br />
 +
**[[4fza]], [[4fzd]], [[4fzf]] – hChk Mst4 (mutant) + calcium-binding protein <br />
*'''Chk25'''
*'''Chk25'''
-
**[[2xik]] – hChk25<br />
+
**[[2xik]] – hChk25 kinase domain<br />
-
**[[3w8h]] – hChk25 + programmed cell death protein 10<br />
+
**[[3w8h]] – hChk25 regulatory domain + programmed cell death protein 10<br />
 +
**[[4nzw]] – hChk25 kinase domain (mutant) + calcium-binding protein <br />
*'''Chk32'''
*'''Chk32'''
Line 204: Line 224:
**[[1uwj]] – hB-Raf kinase domain (mutant) + anticancer drug<br />
**[[1uwj]] – hB-Raf kinase domain (mutant) + anticancer drug<br />
**[[2fb8]], [[3d4q]], [[3ii5]], [[3psd]], [[3skc]], [[3tv6]], [[4g9c]], [[4ksp]], [[4ksq]], [[3psb]], [[3ppj]], [[3ppk]], [[3prf]], [[3pri]], [[3tv4]], [[4dbn]], [[4e4x]], [[4mbj]], [[4ehe]], [[3q4c]], [[3q96]], [[3e26]], [[4h58]], [[4e26]], [[4fc0]], [[4pp7]] – hB-Raf kinase domain + pyrazole inhibitor<br />
**[[2fb8]], [[3d4q]], [[3ii5]], [[3psd]], [[3skc]], [[3tv6]], [[4g9c]], [[4ksp]], [[4ksq]], [[3psb]], [[3ppj]], [[3ppk]], [[3prf]], [[3pri]], [[3tv4]], [[4dbn]], [[4e4x]], [[4mbj]], [[4ehe]], [[3q4c]], [[3q96]], [[3e26]], [[4h58]], [[4e26]], [[4fc0]], [[4pp7]] – hB-Raf kinase domain + pyrazole inhibitor<br />
-
**[[4jvg]], [[4ehg]], [[4fk3]], [[3idp]], [[4g9r]] – hB-Raf kinase domain (mutant) + pyrazole inhibitor<br />
+
**[[4jvg]], [[4ehg]], [[4fk3]], [[3idp]], [[4g9r]], [[4wo5]], [[4mnf]] – hB-Raf kinase domain (mutant) + pyrazole inhibitor<br />
 +
**[[4mne]] – hB-Raf kinase domain + MAPKK1<br />
**[[2l05]] – hB-Raf RAS-binding domain - NMR<br />
**[[2l05]] – hB-Raf RAS-binding domain - NMR<br />
**[[3ny5]] – hB-Raf RAS-binding domain <br />
**[[3ny5]] – hB-Raf RAS-binding domain <br />
Line 237: Line 258:
*'''hChk Pak'''
*'''hChk Pak'''
-
**[[1f3m]] – hChk Pak-1<br />
+
**[[1f3m]] – hChk Pak-1 autoregulatory+kinase domains<br />
-
**[[1yhv]], [[1yhw]], [[3q4z]], [[3q52]], [[3q53]] – hChk Pak-1 (mutant)<br />
+
**[[4otd]] - hChk Pak-1 catalytic domain<br />
-
**[[4daw]] – hChk Pak-1 (mutant) + Ru phthalimide<br />
+
**[[1yhv]], [[1yhw]], [[3q4z]], [[3q52]], [[3q53]] – hChk Pak-1 kinase domain (mutant)<br />
-
**[[4o0r]], [[4o0t]] – hChk Pak-1 + inhibitor<br />
+
**[[4o0r]], [[4o0t]] – hChk Pak-1 kinase domain + inhibitor<br />
-
**[[4eqc]] – hChk Pak-1 (mutant) + inhibitor<br />
+
**[[4oti]], [[4oth]], [[4otg]] – hChk Pak-1 catalytic domain + inhibitor<br />
-
**[[2hy8]] – hChk Pak-1 + staurosporin<br />
+
**[[4eqc]], [[4p90]] – hChk Pak-1 kinase domain (mutant) + inhibitor<br />
 +
**[[2hy8]] – hChk Pak-1 kinase domain + staurosporin<br />
**[[2qme]] – hChk Pak-1 CRIB domain + RAC3<br />
**[[2qme]] – hChk Pak-1 CRIB domain + RAC3<br />
-
**[[3fxz]], [[3fy0]] – hChk Pak-1 kinase domain (mutant) + Ru complex<br />
+
**[[3fxz]], [[3fy0]], [[4daw]] – hChk Pak-1 kinase domain (mutant) + Ru complex<br />
**[[2j0i]], [[4fie]] – hChk Pak-4<br />
**[[2j0i]], [[4fie]] – hChk Pak-4<br />
**[[4fig]], [[4fij]], [[4l67]] – hChk Pak-4 kinase domain<br />
**[[4fig]], [[4fij]], [[4l67]] – hChk Pak-4 kinase domain<br />
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**[[2ov2]] – hChk Pak-4 CRIB domain + RAC3<br />
**[[2ov2]] – hChk Pak-4 CRIB domain + RAC3<br />
**[[2qon]], [[4fif]], [[4fih]], [[4fii]], [[4jdh]], [[4jdi]], [[4jdj]], [[4jdk]] – hChk Pak-4 kinase domain + peptide<br />
**[[2qon]], [[4fif]], [[4fih]], [[4fii]], [[4jdh]], [[4jdi]], [[4jdj]], [[4jdk]] – hChk Pak-4 kinase domain + peptide<br />
-
**[[4app]], [[4o0v]], [[4o0x]], [[4o0y]] – hChk Pak-4 kinase domain + inhibitor<br />
+
**[[4app]], [[4o0v]], [[4o0x]], [[4o0y]], [[4njd]] – hChk Pak-4 kinase domain + inhibitor<br />
**[[2x4z]], [[2xh5]] – hChk Pak-4 kinase domain (mutant) + inhibitor<br />
**[[2x4z]], [[2xh5]] – hChk Pak-4 kinase domain (mutant) + inhibitor<br />
**[[2c30]] – hChk Pak-6<br />
**[[2c30]] – hChk Pak-6<br />
Line 260: Line 282:
*'''Mycobacterium tuberculosis Chk Pkn'''
*'''Mycobacterium tuberculosis Chk Pkn'''
-
**[[3ori]], [[3ork]], [[3orl]], [[3orm]], [[3oro]], [[3orp]], [[3ort]] - MtChk PknB kinase domain (mutant) – ''Mycobacterium tuberculosis''<br />
+
**[[4x3f]] - MtChk PknA – ''Mycobacterium tuberculosis''<br />
 +
**[[4ow8]] - MtChk PknA kinase domain <br />
 +
**[[3ori]], [[3ork]], [[3orl]], [[3orm]], [[3oro]], [[3orp]], [[3ort]] - MtChk PknB kinase domain (mutant) <br />
**[[3ouv]] - MtChk PknB extracellular domain<br />
**[[3ouv]] - MtChk PknB extracellular domain<br />
**[[1o6y]] – MtChk PknB catalytic domain<br />
**[[1o6y]] – MtChk PknB catalytic domain<br />
Line 267: Line 291:
**[[1rwi]], [[1rwl]] - MtChk PknD extracellular domain<br />
**[[1rwi]], [[1rwl]] - MtChk PknD extracellular domain<br />
**[[2h34]] – MtChk PknE catalytic domain<br />
**[[2h34]] – MtChk PknE catalytic domain<br />
 +
**[[4y12]] - MtChk PknG + ATP-gS<br />
 +
**[[4y0x]] - MtChk PknG + ADP<br />
**[[4esq]] - MtChk PknH extracellular domain<br />
**[[4esq]] - MtChk PknH extracellular domain<br />
Line 296: Line 322:
**[[2vuw]], [[2wb8]] – hChk Haspin kinase domain <br />
**[[2vuw]], [[2wb8]] – hChk Haspin kinase domain <br />
**[[3dle]] – hChk Haspin kinase domain + AMP<br />
**[[3dle]] – hChk Haspin kinase domain + AMP<br />
-
**[[3e7v]], [[3f2n]], [[3fmd]], [[3iq7]] – hChk Haspin kinase domain + inhibitor<br />
+
**[[3e7v]], [[3f2n]], [[3fmd]], [[3iq7]], [[4qtc]] – hChk Haspin kinase domain + inhibitor<br />
**[[4ouc]] – hChk Haspin kinase domain + histone H3 peptide<br />
**[[4ouc]] – hChk Haspin kinase domain + histone H3 peptide<br />
Line 313: Line 339:
**[[3e7e]] – hChk Bub1 residues 724-1025<br />
**[[3e7e]] – hChk Bub1 residues 724-1025<br />
**[[3si5]] – hChk Bub1 residues 67-220 + CASC5 peptide<br />
**[[3si5]] – hChk Bub1 residues 67-220 + CASC5 peptide<br />
 +
**[[4r8q]], [[4qpm]] – hChk Bub1 kinase domain + ADP<br />
**[[4a1g]] – hChk Bub1 TPR domain + CASC5 KI motif<br />
**[[4a1g]] – hChk Bub1 TPR domain + CASC5 KI motif<br />
**[[4ggd]] - hChk Bub1 + cell division cycle protein<br />
**[[4ggd]] - hChk Bub1 + cell division cycle protein<br />
Line 357: Line 384:
**[[2v62]] – hChk Vrk2 kinase domain <br />
**[[2v62]] – hChk Vrk2 kinase domain <br />
**[[3dak]] – hChk Osr1 kinase domain <br />
**[[3dak]] – hChk Osr1 kinase domain <br />
-
**[[3fpq]] - hChk Wnk1 kinase domain (mutant)<br />
+
**[[3fpq]], [[4q2a]], [[4pwn]] - hChk Wnk1 kinase domain (mutant)<br />
**[[4aw2]] – hChk Mrckα kinase domain<br />
**[[4aw2]] – hChk Mrckα kinase domain<br />
 +
**[[4pxw]] – hChk Vprbp WD repeat domain (mutant)<br />
**[[1how]], [[1zxe]], [[1zy4]] – yChk (mutant)<br />
**[[1how]], [[1zxe]], [[1zy4]] – yChk (mutant)<br />
**[[1q8z]], [[1zyc]] – yChk <br />
**[[1q8z]], [[1zyc]] – yChk <br />
Line 381: Line 409:
**[[3hdm]], [[3hdn]] – hChk Sgk1 (mutant) + inhibitor <br />
**[[3hdm]], [[3hdn]] – hChk Sgk1 (mutant) + inhibitor <br />
**[[2r5t]] – hChk Sgk3 + AMPPNP <br />
**[[2r5t]] – hChk Sgk3 + AMPPNP <br />
-
**[[2uv2]] – hChk Ste20 + inhibitor <br />
+
**[[4otp]] – hChk Rio1 Rio domain + ADP <br />
**[[2v3s]] – hChk Osr1 + hChk Wnk4 peptide <br />
**[[2v3s]] – hChk Osr1 + hChk Wnk4 peptide <br />
**[[2vwi]] – hChk Osr1 kinase domain + ANP <br />
**[[2vwi]] – hChk Osr1 kinase domain + ANP <br />
-
**[[3ggf]] – hChk Mst4 + inhibitor <br />
 
-
**[[4geh]], [[3w8i]] - hChk Mst4 dimerization domain + programmed cell death protein 10<br />
 
-
**[[4fza]], [[4fzd]], [[4fzf]] – hChk Mst4 (mutant) + calcium-binding protein <br />
 
**[[4crs]] – hChk N2 kinase domain + ATPγS<br />
**[[4crs]] – hChk N2 kinase domain + ATPγS<br />
-
**[[3tku]] – hChk Mrckβ + fasudil<br />
+
**[[3tku]], [[4ual]] – hChk Mrckβ + inhibitor<br />
 +
**[[4uak]] – hChk Mrckβ + ADP<br />
 +
**[[5aja]] – hChk Vprbp WD repeat domain + VPX + SAMHD1<br />
 +
**[[4wzx]] – hChk Ulk3 MIT 2 domain + inhibitor<br />
 +
**[[4wnp]], [[4wno]] – hChk Ulk1 + IST1 homolog<br />
**[[1q8y]], [[1q97]], [[1q99]], [[1zyd]] – yChk + nucleotide<br />
**[[1q8y]], [[1q97]], [[1q99]], [[1zyd]] – yChk + nucleotide<br />
**[[1zy5]] – yChk (mutant) + nucleotide<br />
**[[1zy5]] – yChk (mutant) + nucleotide<br />
**[[2jd5]] – yChk + NPL-3P<br />
**[[2jd5]] – yChk + NPL-3P<br />
 +
**[[4lqs]], [[4lqq]], [[4lqp]] – yChk Cbk1 residues 251-756 + Cbk1 activator Mob2<br />
**[[3p86]], [[3ppz]] - AtChk Ctr1 + staurosporin<br />
**[[3p86]], [[3ppz]] - AtChk Ctr1 + staurosporin<br />
**[[3tpt]] – EcChk Hipa (mutant) + ADP<br />
**[[3tpt]] – EcChk Hipa (mutant) + ADP<br />

Revision as of 10:58, 15 June 2015

Crystal Structure of Glycogen Synthase Kinase 3ß bound to Anticancer Ruthenium Complex

Drag the structure with the mouse to rotate

3D structures of serine/threonine protein kinase

Updated on 15-June-2015


References

  1. ↑ Atilla-Gokcumen GE, Di Costanzo L, Meggers E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3beta. J Biol Inorg Chem. 2010 Sep 7. PMID:20821241 doi:10.1007/s00775-010-0699-x

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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