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Virus protease
From Proteopedia
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**[[2h9h]] – HAVP residues 1520-1731 (mutant) + polypeptide inhibitor | **[[2h9h]] – HAVP residues 1520-1731 (mutant) + polypeptide inhibitor | ||
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| + | *'''Hepatitis C virus protease''' | ||
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| + | **[[2o8m]] – HCVP (mutant)<br /> | ||
*'''Orf 17''' | *'''Orf 17''' | ||
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**[[4izj]], [[4izk]] – YAV Vp4 (mutant) – yellowtail ascites virus | **[[4izj]], [[4izk]] – YAV Vp4 (mutant) – yellowtail ascites virus | ||
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| + | *'''Pseudorabies virus protease''' | ||
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| + | **[[4cx8]] – YAV – pseudorabies virus<br /> | ||
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}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:34, 25 June 2015
Virus proteases include HIV protease, XMRV protease, retropepsin.
HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa.
See also
- Human Immunodeficiency Virus
- HIV-1 protease
- HIV Protease Inhibitor Pharmacokinetics
- HIV Protease Inhibitor Resistance Profile
- HIV Protease Resistance
- Molecular Playground/Dengue Virus Protease
- Viability of a drug-resistant HIV-1 protease mutant
- Molecular Playground/Dengue Virus Protease
3D Structures of Virus proteases
Updated on 25-June-2015
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
