Cardiotoxin
From Proteopedia
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== Function == | == Function == | ||
| - | [[Cardiotoxin]] (CTX) is a snake toxin from the Taiwan cobra ''Naja naja''. The cardiotoxin from the Malayan krait is called '''bucain'''. CTX perturb the membrane structure of cells by interaction with lipids. | + | [[Cardiotoxin]] (CTX) is a snake toxin from the Taiwan cobra ''Naja naja''. The cardiotoxin from the Malayan krait is called '''bucain'''. CTX perturb the membrane structure of cells by interaction with lipids. <ref>PMID:3472200</ref> For toxins in Proteopedia see [[Toxins]].<br /> |
== Relevance == | == Relevance == | ||
Revision as of 13:27, 19 November 2015
Function
Cardiotoxin (CTX) is a snake toxin from the Taiwan cobra Naja naja. The cardiotoxin from the Malayan krait is called bucain. CTX perturb the membrane structure of cells by interaction with lipids. [1] For toxins in Proteopedia see Toxins.
Relevance
Cardiotoxin I causes necrosis of skeletal muscle cells. Cardiotoxin III induces apoptosis in K562 cells.
3D Structures of Cardiotoxin
Updated on 19-November-2015
2cdx - NaCTX I – NMR – Naja atra
4om4 - NaCTX II
1cre, 1crf - NaCTX II – NMR
2ccx – NmCTX II – Naja mossambica – NMR
1cdt – NmCTX II
1ffj, 1cb9, 1ccq – CTX II – Naja oxiana – NMR
1i02, 2crs, 2crt - NaCTX III – NMR
1xt3, 1h0j – NaCTX III
4om5 - NaCTX IV
1kbs, 1kbt - NaCTX IV – NMR
1chv, 1cvo – NaCTX V – NMR
1kxi - NaCTX V
1ug4 – CTX VI
3plc – β-CTX – king cobra
1cxn, 1cxo, 1tgx – γ-CTX – Naja nigricollis - NMR
2h8u – Bucain
2bhi – CTX III+sulfogalactoceramide
