Fibrin

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{{STRUCTURE_1n73| PDB=1n73 | SIZE=350| SCENE=Fibrin/Cv/2 |right|CAPTION=Fibrin α1 subunit (red, yellow), β subunit (Green, blue), γ subunit (orange, magenta) from ''Petromyzon marinus'', [[1n73]] }}
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<StructureSection load='1n73' size='350' side='right' scene='Fibrin/Cv/2' caption='Fibrin α1 subunit (red, yellow), β subunit (Green, blue), γ subunit (orange, magenta) from ''Petromyzon marinus'', [[1n73]]'>
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== Function ==
== Function ==
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Overexpression of FIa can cause thrombosis.
Overexpression of FIa can cause thrombosis.
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</StructureSection>
== 3D Structures of Fibrin ==
== 3D Structures of Fibrin ==

Revision as of 09:25, 21 February 2016

PDB ID 1n73

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3D Structures of Fibrin

Updated on 21-February-2016

3h32 – hFIa peptide+ hFI α, β, γ chains – human
2q9i, 2z4e - hFIa B-knob+ hFI α, β, γ chains
2hlo, 1n86 - hFIa α, β, γ chains + peptide
1n8e - hFIa α, β, γ chains
1n73 - FIa α, β, γ chains + peptide – Sea lamprey
1fzc – hDDFIa+peptide

References

  1. Yang Z, Pandi L, Doolittle RF. The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface. Biochemistry. 2002 Dec 31;41(52):15610-7. PMID:12501189

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Alexander Berchansky, Michal Harel

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