Sandbox reserved 1169
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
<StructureSection load='4grv' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='4grv' size='340' side='right' caption='Caption for this structure' scene=''> | ||
== Introduction == | == Introduction == | ||
| - | The neurotensin receptor (NTSR1) belongs to the superfamily of proteins known as G protein-coupled receptors(link to g protein page in proteopedia) and responds to the 13 amino acid hormone nuerotensin (NT). There are currently around 800 G protein-coupled receptors that have been identified | + | The neurotensin receptor (NTSR1) belongs to the superfamily of proteins known as G protein-coupled receptors(link to g protein page in proteopedia) and responds to the 13 amino acid hormone nuerotensin (NT). There are currently around 800 G protein-coupled receptors that have been identified and they are thought to be responsible for roughly 80% of signal transduction across the cell membrane.(reference (year in g protein) These receptors have been found to be involved in a vast array of physiological processes within the body and are a major site of drug targets in medicine. (reference 5 main families) |
== Neurotensin == | == Neurotensin == | ||
== Structure == | == Structure == | ||
Revision as of 18:51, 28 March 2016
Neurotensin Receptor (Rattus norvegicus)
| |||||||||||
References
Millar, Robert P., and Claire L. Newton. "The year in G protein-coupled receptor research." Molecular endocrinology 24.1 (2010): 261-274.
Fredriksson, Robert, et al. "The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints." Molecular pharmacology 63.6 (2003): 1256-1272.
