This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Methyl CpG binding protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 33: Line 33:
**[[2l2l]] - hMBD2 coiled-coil domain + transcriptional repressor p66-α coiled-coil domain – NMR<br />
**[[2l2l]] - hMBD2 coiled-coil domain + transcriptional repressor p66-α coiled-coil domain – NMR<br />
 +
**[[2ky8]] – cMBD2 MBD domain + DNA containing cytidine and uridine derivatives - NMR - chicken<br />
*Methyl CpG binding protein 3 (MBD3)
*Methyl CpG binding protein 3 (MBD3)
Line 56: Line 57:
**[[1qk9]] - hMeCP2 MBD domain – NMR<br />
**[[1qk9]] - hMeCP2 MBD domain – NMR<br />
**[[3c2i]] – hMeCP2 MBD domain (mutant) + DNA<br />
**[[3c2i]] – hMeCP2 MBD domain (mutant) + DNA<br />
-
**[[1ub1]] – cMeCP2 attachment-region binding domain – chicken – NMR<br />
+
**[[1ub1]] – cMeCP2 attachment-region binding domain – NMR<br />
-
**[[2ky8]] – cMBD4 MBD + DNA containing cytidine and uridine derivatives - NMR<br />
+
}}
}}

Revision as of 09:04, 24 April 2016

Structure of mouse MBD4 glycosylate domain complex with DNA containing mismatch, ethylene glycol and Ni+2 ion (green) (PDB code 4evv).

Drag the structure with the mouse to rotate

3D structures of methyl CpG binding protein

Updated on 24-April-2016

References

  1. ↑ Wade PA. Methyl CpG-binding proteins and transcriptional repression. Bioessays. 2001 Dec;23(12):1131-7. PMID:11746232 doi:http://dx.doi.org/10.1002/bies.10008
  2. ↑ Van den Veyver IB, Zoghbi HY. Mutations in the gene encoding methyl-CpG-binding protein 2 cause Rett syndrome. Brain Dev. 2001 Dec;23 Suppl 1:S147-51. PMID:11738862
  3. ↑ Hashimoto H, Zhang X, Cheng X. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Res. 2012 Jun 27. PMID:22740654 doi:10.1093/nar/gks628

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Methyl_CpG_binding_protein"
Personal tools