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You may include any references to papers as in: the use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Function

DNA Gyrase is a protein located mainly in Prokaryotes, specifically bacteria. It falls under the Topoisomerase family and can be referred to as Topoisomerase II. It is responsible for negatively induced supercoiling. This method of supercoiling is used to reduce the strain caused by the twists in DNA. It aids in compaction, as well as separation of DNA. As one can see, it plays a significant role in prokaryotes.

Disease:Topoisomerase II Alpha

Researches specifically study this protein for multiple reasons. It could possibly help with antibacterial chemotherapy.

Relevance

Structural highlights

The structure of DNA Gyrase consists of mainly two subunits. This First known as A contains the tyrosine which is responsible for cleavage. The second subunit B is responsible to the binding of ATPase’s active site. Both subunits work together to produce the negative supercoiling produced in DNA strands.

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.