Sandbox Reserved 1408
From Proteopedia
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==1bna Structure== | ==1bna Structure== | ||
| - | <Structure load=' | + | <Structure load='1tup' size='350' frame='true' align='right' caption='p53 protein with DNA' scene='' /> |
| - | + | Protein p53 is made of 393 amino acids, consisting of seven domains. These domains include proline rich domain, activation domain 2, transcription activation domain, DNA-binding core domain, C-terminal domain, tetramerzatin domain, and a nuclear localization signaling domain. | |
== Function == | == Function == | ||
| + | Protein p53 is a transcription factor that regulates DNA repair, cell arrest, and apoptosis by <scene name='77/777728/1tup_binds_to_dna/1'>binding to genes</scene>. It is activated in response to stressors including radiation, oxidation stress, porto-oncogenes, and DNA-damaging agents. | ||
| - | == | + | == Significance == |
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| - | <scene name='77/777728/Purines_of_1bna/1'>purines</scene> of 1bna | ||
== References == | == References == | ||
Revision as of 20:40, 12 February 2018
| This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430. |
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Contents |
1bna Structure
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Protein p53 is made of 393 amino acids, consisting of seven domains. These domains include proline rich domain, activation domain 2, transcription activation domain, DNA-binding core domain, C-terminal domain, tetramerzatin domain, and a nuclear localization signaling domain.
Function
Protein p53 is a transcription factor that regulates DNA repair, cell arrest, and apoptosis by . It is activated in response to stressors including radiation, oxidation stress, porto-oncogenes, and DNA-damaging agents.
