5mux
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of 2-methylcitrate dehydratase (MmgE) from Bacillus subtilis.== | |
- | + | <StructureSection load='5mux' size='340' side='right' caption='[[5mux]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5mux]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MUX FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mux OCA], [http://pdbe.org/5mux PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mux RCSB], [http://www.ebi.ac.uk/pdbsum/5mux PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mux ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/PRPD_BACSU PRPD_BACSU]] Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the stereospecific dehydration of (2S,3S)-2-methylcitrate (2-MC) to yield the cis isomer of 2-methyl-aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate.[UniProtKB:P77243] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Baker, G E]] | ||
+ | [[Category: Race, P R]] | ||
+ | [[Category: Dehydratase]] | ||
+ | [[Category: Lyase]] |
Revision as of 06:21, 15 February 2018
Crystal structure of 2-methylcitrate dehydratase (MmgE) from Bacillus subtilis.
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