1th6
From Proteopedia
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==Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution== | ==Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution== | ||
<StructureSection load='1th6' size='340' side='right' caption='[[1th6]], [[Resolution|resolution]] 1.23Å' scene=''> | <StructureSection load='1th6' size='340' side='right' caption='[[1th6]], [[Resolution|resolution]] 1.23Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1th6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1th6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Daboia_russellii_russellii Daboia russellii russellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TH6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OIN:(1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL+(2R)-3-HYDROXY-2-PHENYLPROPANOATE'>OIN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OIN:(1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL+(2R)-3-HYDROXY-2-PHENYLPROPANOATE'>OIN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q7a|1q7a]], [[1sv3|1sv3]], [[1tg1|1tg1]], [[1tg4|1tg4]], [[1tgm|1tgm]], [[1ti0|1ti0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q7a|1q7a]], [[1sv3|1sv3]], [[1tg1|1tg1]], [[1tg4|1tg4]], [[1tgm|1tgm]], [[1ti0|1ti0]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1th6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1th6 OCA], [http://pdbe.org/1th6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1th6 RCSB], [http://www.ebi.ac.uk/pdbsum/1th6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1th6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1th6 OCA], [http://pdbe.org/1th6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1th6 RCSB], [http://www.ebi.ac.uk/pdbsum/1th6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1th6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1th6_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1th6_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Daboia russellii russellii]] |
[[Category: Betzel, C]] | [[Category: Betzel, C]] | ||
[[Category: Jabeen, T]] | [[Category: Jabeen, T]] | ||
Revision as of 07:59, 14 March 2018
Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution
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Categories: Daboia russellii russellii | Betzel, C | Jabeen, T | Pal, A | Perbandt, M | Sharma, S | Singh, N | Singh, T P | Eicosanoid | Hydrolase | Inhibition | Phospholipid
