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Complexin

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[1kil]] – rCPLX + Vamp2 + Syntaxin 1A + Snap25 – rat
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[[1kil]] – rCPLX + Vamp2 + Syntaxin 1A + Snap25 – rat<br />
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[[3rk3]], [[3rl0]] - CPLX + Vamp2 + Syntaxin 1A + Snap25 – human<br />
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[[3rk3]], [[3rl0]] - CPLX + Vamp2 + Syntaxin 1A + Snap25 – human
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-
 
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[[5w5c]], [[5w5d]] - CPLX + Vamp2 + Syntaxin 1A + Snap25 + synaptotagmin <br />
[[5w5c]], [[5w5d]] - CPLX + Vamp2 + Syntaxin 1A + Snap25 + synaptotagmin <br />
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:04, 15 April 2018

Human complexin (magenta) as part of the SNARE complex (VAMP2 - cyan; syntaxin - green; SNAP25 (pink and yellow) (PDB entry 3rk3)

Drag the structure with the mouse to rotate

3D structures of complexin

Updated on 15-April-2018

1kil – rCPLX + Vamp2 + Syntaxin 1A + Snap25 – rat
3rk3, 3rl0 - CPLX + Vamp2 + Syntaxin 1A + Snap25 – human
5w5c, 5w5d - CPLX + Vamp2 + Syntaxin 1A + Snap25 + synaptotagmin

References

  1. Hu K, Carroll J, Rickman C, Davletov B. Action of complexin on SNARE complex. J Biol Chem. 2002 Nov 1;277(44):41652-6. Epub 2002 Aug 27. PMID:12200427 doi:http://dx.doi.org/10.1074/jbc.M205044200
  2. Kummel D, Krishnakumar SS, Radoff DT, Li F, Giraudo CG, Pincet F, Rothman JE, Reinisch KM. Complexin cross-links prefusion SNAREs into a zigzag array. Nat Struct Mol Biol. 2011 Jul 24;18(8):927-33. doi: 10.1038/nsmb.2101. PMID:21785414 doi:10.1038/nsmb.2101

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Michal Harel, Alexander Berchansky

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