Deoxycytidine kinase
From Proteopedia
(Difference between revisions)
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**[[2no9]], [[2noa]], [[2no0]], [[2no6]], [[2zi9]] – hDCK (mutant) + ADP + chemotherapy agent <br /> | **[[2no9]], [[2noa]], [[2no0]], [[2no6]], [[2zi9]] – hDCK (mutant) + ADP + chemotherapy agent <br /> | ||
**[[2zia]], [[4kcg]] – hDCK (mutant) + UDP + chemotherapy agent <br /> | **[[2zia]], [[4kcg]] – hDCK (mutant) + UDP + chemotherapy agent <br /> | ||
| + | **[[5mqi]], [[5mqt]] – hDCK (mutant) + UDP + dCMP + chemotherapy agent<br /> | ||
*dCK complex with nucleoside | *dCK complex with nucleoside | ||
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**[[3qeo]] – hDCK (mutant) + UDP + dT<br /> | **[[3qeo]] – hDCK (mutant) + UDP + dT<br /> | ||
**[[2a30]] – hDCK (mutant) + dC<br /> | **[[2a30]] – hDCK (mutant) + dC<br /> | ||
| + | **[[5mqj]] – hDCK (mutant) + UDP + UMP<br /> | ||
*Other dCK complexes | *Other dCK complexes | ||
Revision as of 10:13, 23 April 2018
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3D Structures of deoxycytidine kinase
Updated on 23-April-2018
References
- ↑ Hazra S, Ort S, Konrad M, Lavie A. Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues . Biochemistry. 2010 Aug 10;49(31):6784-90. PMID:20614893 doi:10.1021/bi100839e
- ↑ Sabini E, Ort S, Monnerjahn C, Konrad M, Lavie A. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nat Struct Biol. 2003 Jul;10(7):513-9. PMID:12808445 doi:http://dx.doi.org/10.1038/nsb942
