2cig
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==Dihydrofolate reductase from Mycobacterium tuberculosis inhibited by the acyclic 4R isomer of INH-NADP a derivative of the prodrug isoniazid.== | ||
<StructureSection load='2cig' size='340' side='right' caption='[[2cig]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2cig' size='340' side='right' caption='[[2cig]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1df7|1df7]], [[1dg5|1dg5]], [[1dg7|1dg7]], [[1dg8|1dg8]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1df7|1df7]], [[1dg5|1dg5]], [[1dg7|1dg7]], [[1dg8|1dg8]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cig OCA], [http://pdbe.org/2cig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cig RCSB], [http://www.ebi.ac.uk/pdbsum/2cig PDBsum], [http://www.topsan.org/Proteins/TBSGC/2cig TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cig OCA], [http://pdbe.org/2cig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cig RCSB], [http://www.ebi.ac.uk/pdbsum/2cig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cig ProSAT], [http://www.topsan.org/Proteins/TBSGC/2cig TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/2cig_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/2cig_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Revision as of 08:03, 23 May 2018
Dihydrofolate reductase from Mycobacterium tuberculosis inhibited by the acyclic 4R isomer of INH-NADP a derivative of the prodrug isoniazid.
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