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Virus protease

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Line 42: Line 42:
**[[2b7f]] – HTLV-PV + peptide<br />
**[[2b7f]] – HTLV-PV + peptide<br />
-
**[[3lin]] – HTLV-PV (mutant) + inhibitor<br />
+
**[[3lin]], [[3liq]], [[3lit]], [[3liv]], [[3lix]], [[3liy]], [[4ydg]], [[4ydf]] – HTLV-PV (mutant) + inhibitor<br />
*'''Rous sarcoma virus protease'''
*'''Rous sarcoma virus protease'''
-
**[[1bai]] – RSVP + polypeptide inhibitor _ Rous sarcoma virus
+
**[[2rsp]] – RSVP - Rous sarcoma virus<br/>
 +
**[[1bai]] – RSVP + polypeptide inhibitor
*'''Human Cytomegalovirus protease'''
*'''Human Cytomegalovirus protease'''
-
**[[1cmv]], [[1lay]] – CMVP (mutant) – human herpes virus 5<br />
+
**[[1wpo]] – CMVP - human herpes virus 5<br />
-
**[[1wpo]] – CMVP<br />
+
**[[1cmv]], [[1lay]], [[1jq6]], [[1id4]], [[1iec]], [[1ied]], [[1ief]], [[1ieg]] – CMVP (mutant) <br />
-
**[[2wpo]] - CMVP (mutant) + inhibitor
+
**[[2wpo]], [[1jq7]] - CMVP (mutant) + inhibitor<br />
 +
**[[1njt]], [[1nju]], [[1nkk]], [[1nkm]] - CMVP (mutant) + peptide inhibitor<br />
*'''Varicella-Zoster virus protease'''
*'''Varicella-Zoster virus protease'''
Line 60: Line 62:
*'''Equine infectious anemia virus protease'''
*'''Equine infectious anemia virus protease'''
-
**[[2fmb]] – EIAVP (mutant) + inhibitor
+
**[[2fmb]], [[1fmb]] – EIAVP (mutant) + inhibitor
*'''Hepatitis A virus protease'''
*'''Hepatitis A virus protease'''
-
**[[2h9h]] – HAVP residues 1520-1731 (mutant) + polypeptide inhibitor
+
**[[2h9h]], [[2hal]] – HAVP residues 1520-1731 (mutant) + polypeptide inhibitor
*'''Hepatitis C virus protease'''
*'''Hepatitis C virus protease'''
**[[2o8m]] – HCVP (mutant)<br />
**[[2o8m]] – HCVP (mutant)<br />
 +
**[[2a4g]], [[2gvf]], [[2f9u]], [[2f9v]] – HCVP + peptide inhibitor<br />
*'''Orf 17'''
*'''Orf 17'''
Line 78: Line 81:
**[[3u1i]] – DvNs2b + peptide – Dengue virus<br />
**[[3u1i]] – DvNs2b + peptide – Dengue virus<br />
**[[3u1j]] – DvNs2b + BPTI<br />
**[[3u1j]] – DvNs2b + BPTI<br />
-
**[[2fom]] - DvNs2b + DvNs3<br />
+
**[[2fom]] - DvNs2b/DvNs3<br />
-
**[[2whx]] – DvNs3 residues 1475-2092
+
**[[4m9f]], [[4m9i]], [[4m9k]], [[4m9m]], [[3lkw]] - DvNs2b/DvNs3 (mutant)<br />
 +
**[[4m9t]] - DvNs2b/DvNs3 (mutant) + inhibitor<br />
 +
**[[2jlq]] – DvNs3 residues 1646-2092 <br />
 +
**[[2jlv]] – DvNs3 residues 1646-2092 + AMPPNP + RNA<br />
 +
**[[2jlr]] – DvNs3 residues 1646-2092 + AMPPNP<br />
 +
**[[2jls]] – DvNs3 residues 1646-2092 + ADP<br />
 +
**[[2jlx]], [[2jly]], [[2jlz]] – DvNs3 residues 1646-2092 + ADP + RNA<br />
 +
**[[2jlu]], [[2jlw]] – DvNs3 residues 1646-2092 + RNA<br />
 +
**[[2vbc]], [[2whx]], [[2wzq]] – DvNs3 residues 1475-2092 + peptide inhibitor<br />
 +
**[[2m9p]], [[2m9q]] – DvNs3 residues 1475-1648 + peptide inhibitor - NMR<br />
*'''Herpes simplex virus protease'''
*'''Herpes simplex virus protease'''

Revision as of 22:59, 5 October 2018

HIV-1 protease dimer complex with tert-butylcarbonate (PDB entry 1odw)

Drag the structure with the mouse to rotate

3D Structures of Virus proteases

Updated on 05-October-2018

References

  1. ↑ Tong L. Viral proteases. Chem Rev. 2002 Dec;102(12):4609-26. PMID:12475203

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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