Virus protease
From Proteopedia
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**[[3zv9]], [[3zva]], [[3zvb]], [[3zvc]], [[3zvd]], [[3zve]], [[3zvf]], [[3zvg]] – HEVP 68 + inhibitor <br /> | **[[3zv9]], [[3zva]], [[3zvb]], [[3zvc]], [[3zvd]], [[3zve]], [[3zvf]], [[3zvg]] – HEVP 68 + inhibitor <br /> | ||
| - | '''Porcine epidemic diarrhea virus protease''' | + | *'''Porcine epidemic diarrhea virus protease''' |
**[[5hyo]] – PEDVP – porcine epidemic diarrhea virus <br /> | **[[5hyo]] – PEDVP – porcine epidemic diarrhea virus <br /> | ||
| - | '''Coronavirus protease''' | + | *'''Coronavirus protease''' |
**[[4wme]], [[4wmf]] – CVP (mutant)- coronavirus <br /> | **[[4wme]], [[4wmf]] – CVP (mutant)- coronavirus <br /> | ||
| - | '''SARS coronavirus protease''' | + | *'''SARS coronavirus protease''' |
**[[3e91]], [[3ea7]], [[3ea8]], [[3ea9]], [[3eaj]] – SCVP (mutant) – SARS coronavirus <br /> | **[[3e91]], [[3ea7]], [[3ea8]], [[3ea9]], [[3eaj]] – SCVP (mutant) – SARS coronavirus <br /> | ||
**[[2amd]], [[2amq]], [[2gx4]], [[2z9g]], [[2z9j]], [[2z9k]], [[2z9l]], [[2zu5]], [[4mds]], [[4tww]], [[4twy]] – SCVP + inhibitor <br /> | **[[2amd]], [[2amq]], [[2gx4]], [[2z9g]], [[2z9j]], [[2z9k]], [[2z9l]], [[2zu5]], [[4mds]], [[4tww]], [[4twy]] – SCVP + inhibitor <br /> | ||
| - | '''Coronavirus HKU4 protease''' | + | *'''Coronavirus HKU4 protease''' |
**[[2ynb]] – CVHP + inhibitor – BAT coronavirus <br /> | **[[2ynb]] – CVHP + inhibitor – BAT coronavirus <br /> | ||
| - | '''Echovirus 1 protease''' | + | *'''Echovirus 1 protease''' |
**[[5iyt]] – EV1P (mutant) + inhibitor – Echovirus 1 <br /> | **[[5iyt]] – EV1P (mutant) + inhibitor – Echovirus 1 <br /> | ||
| - | '''Norovirus protease''' | + | *'''Norovirus protease''' |
**[[5e0g]], [[5e0h]], [[5e0j]] – NVP (mutant)+ peptide inhibitor – Norovirus <br /> | **[[5e0g]], [[5e0h]], [[5e0j]] – NVP (mutant)+ peptide inhibitor – Norovirus <br /> | ||
**[[3ur9]], [[4imq]], [[4xbb]], [[4xbc]], [[4xbd]], [[5dg6]], [[5dgj]], [[5tg1]], [[5tg2]] – NVP residues 1101-1281 + inhibitor <br /> | **[[3ur9]], [[4imq]], [[4xbb]], [[4xbc]], [[4xbd]], [[5dg6]], [[5dgj]], [[5tg1]], [[5tg2]] – NVP residues 1101-1281 + inhibitor <br /> | ||
| - | '''Norovirus 3C-like protease''' | + | *'''Norovirus 3C-like protease''' |
**[[1wqs]] – NVLP – chiba virus <br /> | **[[1wqs]] – NVLP – chiba virus <br /> | ||
| - | '''Gastroentritis virus protease''' | + | *'''Gastroentritis virus protease''' |
**[[2amp]] – GEVP + inhibitor – gastroenteritis virus <br /> | **[[2amp]] – GEVP + inhibitor – gastroenteritis virus <br /> | ||
| - | '''Southampton virus protease''' | + | *'''Southampton virus protease''' |
**[[2iph]] – SVP + inhibitor – Southampton virus <br /> | **[[2iph]] – SVP + inhibitor – Southampton virus <br /> | ||
| - | '''West Nile virus protease''' | + | *'''West Nile virus protease''' |
**[[2ggv]] - WNVP (mutant) - West Nile virus<br /> | **[[2ggv]] - WNVP (mutant) - West Nile virus<br /> | ||
Revision as of 17:41, 8 October 2018
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3D Structures of Virus proteases
Updated on 08-October-2018
References
- ↑ Wanga QM, Chen SH. Human rhinovirus 3C protease as a potential target for the development of antiviral agents. Curr Protein Pept Sci. 2007 Feb;8(1):19-27. PMID:17305557
- ↑ Matthews DA, Dragovich PS, Webber SE, Fuhrman SA, Patick AK, Zalman LS, Hendrickson TF, Love RA, Prins TJ, Marakovits JT, Zhou R, Tikhe J, Ford CE, Meador JW, Ferre RA, Brown EL, Binford SL, Brothers MA, DeLisle DM, Worland ST. Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11000-7. PMID:10500114
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