4qi9
From Proteopedia
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==Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate== | ==Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate== | ||
| - | <StructureSection load='4qi9' size='340' side='right' caption='[[4qi9]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='4qi9' size='340' side='right'caption='[[4qi9]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qi9]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QI9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QI9 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4qi9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QI9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QI9 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q1h|3q1h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q1h|3q1h]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA, y3688, YPO0486, YP_3693 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qi9 OCA], [http://pdbe.org/4qi9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qi9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qi9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qi9 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qi9 OCA], [http://pdbe.org/4qi9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qi9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qi9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qi9 ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Yersinia pestis co92]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
Revision as of 09:19, 24 April 2019
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
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Categories: Dihydrofolate reductase | Large Structures | Yersinia pestis co92 | Anderson, W F | Structural genomic | Joachimiak, A | Kim, Y | Makowska-Grzyska, M | Maltseva, N | Mulligan, R | Shatsman, S | Alpha beta fold | Csgid | National institute of allergy and infectious disease | Niaid | Oxidoreductase-oxidoreductase inhibitor complex
