6uca
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human ZCCHC4 in complex with SAH== | |
| - | + | <StructureSection load='6uca' size='340' side='right'caption='[[6uca]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6uca]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UCA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uca OCA], [http://pdbe.org/6uca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uca RCSB], [http://www.ebi.ac.uk/pdbsum/6uca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uca ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ZCHC4_HUMAN ZCHC4_HUMAN]] rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA (PubMed:30531910). N6-methylation of adenine(4220) in 28S rRNA is required for translation (PubMed:30531910).<ref>PMID:30531910</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gao, L]] | ||
| + | [[Category: Huang, M J]] | ||
| + | [[Category: Li, D X]] | ||
| + | [[Category: Lu, J W]] | ||
| + | [[Category: Ren, W D]] | ||
| + | [[Category: Song, J]] | ||
| + | [[Category: Wang, G G]] | ||
| + | [[Category: 28s rna m6a methyltransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:06, 16 October 2019
Crystal structure of human ZCCHC4 in complex with SAH
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