Sulfatase
From Proteopedia
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<StructureSection load='1vz4' size='340' side='right' caption='Alkylsulfatase complex with succinate and Fe+2 ion (PDB code [[1vz4]])' scene=''> | <StructureSection load='1vz4' size='340' side='right' caption='Alkylsulfatase complex with succinate and Fe+2 ion (PDB code [[1vz4]])' scene=''> | ||
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== Function == | == Function == | ||
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of sulfatase == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Arylsulfatase | ||
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| - | **[[1fsu]] – hAS B – human<br /> | ||
| - | **[[1auk]], [[1n2k]], [[1n2l]] – hAS A<br /> | ||
| - | **[[1e2s]], [[1e3c]], [[1e1z]], [[1e33]] – hAS A (mutant)<br /> | ||
| - | **[[1p49]] – hAS C<br /> | ||
| - | **[[4upi]], [[4upl]] – AS – ''Ruegeria pomeroyi''<br /> | ||
| - | **[[1hdh]] – PaAS – ''Pseudomonas aeruginosa''<br /> | ||
| - | **[[4cxk]], [[4cyr]], [[5aj9]] – PaAS (mutant)<br /> | ||
| - | **[[4cxs]], [[4cys]], [[4cxu]] – PaAS (mutant) + phenylphosphonate<br /> | ||
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| - | *Alkylsulfatase | ||
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| - | **[[1oih]] – PpATSK – ''Pseudomonas putida''<br /> | ||
| - | **[[1oii]] – PpATSK + oxoglutarate + Fe<br /> | ||
| - | **[[1vz4]] – PpATSK + succinate + Fe<br /> | ||
| - | **[[1vz5]] – PpATSK + succinate <br /> | ||
| - | **[[1oij]] – PpATSK + oxoglutarate <br /> | ||
| - | **[[1oik]] – PpATSK + oxoglutarate + Fe + hexanesulfonic acid<br /> | ||
| - | **[[2yhe]] – sec-ATSK – ''Pseudomonas''<br /> | ||
| - | **[[4ffa]] – ATSK – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[5aij]], [[5ajl]] – PaATSK <br /> | ||
| - | **[[5aj9]] – PaATSK (mutant)<br /> | ||
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| - | *Estrone sulfatase | ||
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| - | **[[1p49]] – hES <br /> | ||
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| - | *N-acetylgalactosamine-6-sulfatase | ||
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| - | **[[4fdi]] – hGalNS <br /> | ||
| - | **[[4fdj]] – hGalNS + GalNac<br /> | ||
| - | **[[6s20]] – BtGalNS – ''Bacterioides thetaiotamicron''<br /> | ||
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| - | *Endo-4-o-sulfatase | ||
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| - | **[[6s21]] – BtEOS <br /> | ||
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| - | *2-O-glycosaminoglycan sulfatase | ||
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| - | **[[5g2u]] – BtOGS - ''Bacterioides thetaiotaomicron''<br /> | ||
| - | **[[5g2t]] – BtOGS + disulfo-glucosamine + sulfo-threo-enopyranuronic acid<br /> | ||
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| - | *Iduronate-2-sulfatase | ||
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| - | **[[5fql]], [[6ioz]] – hIS <br /> | ||
| - | **[[5g2t]] – hIS + uronic acid derivative<br /> | ||
| - | **[[5g2v]] – hIS + substrate<br /> | ||
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| - | *Choline sulfatase | ||
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| - | **[[4ug4]], [[6fny]], [[6g5z]] – SmChoS - ''Sinrhizobium melioti''<br /> | ||
| - | **[[6g60]] – SmChoS + choline<br /> | ||
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| - | *Iota-carrageenan sulfatase | ||
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| - | **[[6bia]] – PtICS - ''Pseudal teromonas''<br /> | ||
| - | **[[6boj]], [[6b0k]], [[6b1v]] – PtICS + polysaccharide <br /> | ||
| - | **[[6pt6]] – PfICS + neocarratetraose – ''Pseudoalteromonas fuliginea'' <br /> | ||
| - | **[[6pt9]] – PfICS + neocarrabiose<br /> | ||
| - | **[[6b0j]] – PfICS + neocarrahexose<br /> | ||
| - | **[[6ptk]] – PfICS + sulfate<br /> | ||
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| - | *Kappa carrageenan S1 sulfatase | ||
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| - | **[[6prm]] – PfKCS + <br /> | ||
| - | **[[6psm]] – PfKCS + neocarrabiose<br /> | ||
| - | **[[6pso]] – PfKCS + neocarratetraose <br /> | ||
| - | |||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:42, 11 February 2020
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References
- ↑ Hanson SR, Best MD, Wong CH. Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility. Angew Chem Int Ed Engl. 2004 Nov 5;43(43):5736-63. PMID:15493058 doi:http://dx.doi.org/10.1002/anie.200300632
- ↑ van Loo B, Schober M, Valkov E, Heberlein M, Bornberg-Bauer E, Faber K, Hyvonen M, Hollfelder F. Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester. J Mol Biol. 2018 Feb 16. pii: S0022-2836(18)30081-0. doi:, 10.1016/j.jmb.2018.02.010. PMID:29458126 doi:http://dx.doi.org/10.1016/j.jmb.2018.02.010
- ↑ Genicot SM, Groisillier A, Rogniaux H, Meslet-Cladiere L, Barbeyron T, Helbert W. Discovery of a novel iota carrageenan sulfatase isolated from the marine bacterium Pseudoalteromonas carrageenovora. Front Chem. 2014 Aug 26;2:67. doi: 10.3389/fchem.2014.00067. eCollection 2014. PMID:25207269 doi:http://dx.doi.org/10.3389/fchem.2014.00067
- ↑ Dierks T, Schmidt B, Borissenko LV, Peng J, Preusser A, Mariappan M, von Figura K. Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme. Cell. 2003 May 16;113(4):435-44. PMID:12757705

