Sulfatase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
<StructureSection load='1vz4' size='340' side='right' caption='Alkylsulfatase complex with succinate and Fe+2 ion (PDB code [[1vz4]])' scene=''>
<StructureSection load='1vz4' size='340' side='right' caption='Alkylsulfatase complex with succinate and Fe+2 ion (PDB code [[1vz4]])' scene=''>
-
 
+
__TOC__
== Function ==
== Function ==
Line 23: Line 23:
</StructureSection>
</StructureSection>
-
== 3D Structures of sulfatase ==
 
- 
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
-
{{#tree:id=OrganizedByTopic|openlevels=0|
 
- 
-
*Arylsulfatase
 
- 
-
**[[1fsu]] – hAS B – human<br />
 
-
**[[1auk]], [[1n2k]], [[1n2l]] – hAS A<br />
 
-
**[[1e2s]], [[1e3c]], [[1e1z]], [[1e33]] – hAS A (mutant)<br />
 
-
**[[1p49]] – hAS C<br />
 
-
**[[4upi]], [[4upl]] – AS – ''Ruegeria pomeroyi''<br />
 
-
**[[1hdh]] – PaAS – ''Pseudomonas aeruginosa''<br />
 
-
**[[4cxk]], [[4cyr]], [[5aj9]] – PaAS (mutant)<br />
 
-
**[[4cxs]], [[4cys]], [[4cxu]] – PaAS (mutant) + phenylphosphonate<br />
 
- 
-
*Alkylsulfatase
 
- 
-
**[[1oih]] – PpATSK – ''Pseudomonas putida''<br />
 
-
**[[1oii]] – PpATSK + oxoglutarate + Fe<br />
 
-
**[[1vz4]] – PpATSK + succinate + Fe<br />
 
-
**[[1vz5]] – PpATSK + succinate <br />
 
-
**[[1oij]] – PpATSK + oxoglutarate <br />
 
-
**[[1oik]] – PpATSK + oxoglutarate + Fe + hexanesulfonic acid<br />
 
-
**[[2yhe]] – sec-ATSK – ''Pseudomonas''<br />
 
-
**[[4ffa]] – ATSK – ''Mycobacterium tuberculosis''<br />
 
-
**[[5aij]], [[5ajl]] – PaATSK <br />
 
-
**[[5aj9]] – PaATSK (mutant)<br />
 
- 
-
*Estrone sulfatase
 
- 
-
**[[1p49]] – hES <br />
 
- 
-
*N-acetylgalactosamine-6-sulfatase
 
- 
-
**[[4fdi]] – hGalNS <br />
 
-
**[[4fdj]] – hGalNS + GalNac<br />
 
-
**[[6s20]] – BtGalNS – ''Bacterioides thetaiotamicron''<br />
 
- 
-
*Endo-4-o-sulfatase
 
- 
-
**[[6s21]] – BtEOS <br />
 
- 
-
*2-O-glycosaminoglycan sulfatase
 
- 
-
**[[5g2u]] – BtOGS - ''Bacterioides thetaiotaomicron''<br />
 
-
**[[5g2t]] – BtOGS + disulfo-glucosamine + sulfo-threo-enopyranuronic acid<br />
 
- 
-
*Iduronate-2-sulfatase
 
- 
-
**[[5fql]], [[6ioz]] – hIS <br />
 
-
**[[5g2t]] – hIS + uronic acid derivative<br />
 
-
**[[5g2v]] – hIS + substrate<br />
 
- 
-
*Choline sulfatase
 
- 
-
**[[4ug4]], [[6fny]], [[6g5z]] – SmChoS - ''Sinrhizobium melioti''<br />
 
-
**[[6g60]] – SmChoS + choline<br />
 
- 
-
*Iota-carrageenan sulfatase
 
- 
-
**[[6bia]] – PtICS - ''Pseudal teromonas''<br />
 
-
**[[6boj]], [[6b0k]], [[6b1v]] – PtICS + polysaccharide <br />
 
-
**[[6pt6]] – PfICS + neocarratetraose – ''Pseudoalteromonas fuliginea'' <br />
 
-
**[[6pt9]] – PfICS + neocarrabiose<br />
 
-
**[[6b0j]] – PfICS + neocarrahexose<br />
 
-
**[[6ptk]] – PfICS + sulfate<br />
 
- 
-
*Kappa carrageenan S1 sulfatase
 
- 
-
**[[6prm]] – PfKCS + <br />
 
-
**[[6psm]] – PfKCS + neocarrabiose<br />
 
-
**[[6pso]] – PfKCS + neocarratetraose <br />
 
- 
-
}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:42, 11 February 2020

Alkylsulfatase complex with succinate and Fe+2 ion (PDB code 1vz4)

Drag the structure with the mouse to rotate

References

  1. Hanson SR, Best MD, Wong CH. Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility. Angew Chem Int Ed Engl. 2004 Nov 5;43(43):5736-63. PMID:15493058 doi:http://dx.doi.org/10.1002/anie.200300632
  2. van Loo B, Schober M, Valkov E, Heberlein M, Bornberg-Bauer E, Faber K, Hyvonen M, Hollfelder F. Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester. J Mol Biol. 2018 Feb 16. pii: S0022-2836(18)30081-0. doi:, 10.1016/j.jmb.2018.02.010. PMID:29458126 doi:http://dx.doi.org/10.1016/j.jmb.2018.02.010
  3. Genicot SM, Groisillier A, Rogniaux H, Meslet-Cladiere L, Barbeyron T, Helbert W. Discovery of a novel iota carrageenan sulfatase isolated from the marine bacterium Pseudoalteromonas carrageenovora. Front Chem. 2014 Aug 26;2:67. doi: 10.3389/fchem.2014.00067. eCollection 2014. PMID:25207269 doi:http://dx.doi.org/10.3389/fchem.2014.00067
  4. Dierks T, Schmidt B, Borissenko LV, Peng J, Preusser A, Mariappan M, von Figura K. Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme. Cell. 2003 May 16;113(4):435-44. PMID:12757705

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools