This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Johnson's Monday Lab Sandbox for Insulin Receptor
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | == | + | ==Insulin Receptor== |
<StructureSection load='6sof' size='350' side='right' caption='Insulin Receptor with Four Insulin Bound - 6sof' scene=''> | <StructureSection load='6sof' size='350' side='right' caption='Insulin Receptor with Four Insulin Bound - 6sof' scene=''> | ||
This is a default text for your page '''Johnson's Monday Lab Sandbox for Insulin Receptor'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Johnson's Monday Lab Sandbox for Insulin Receptor'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
| Line 9: | Line 9: | ||
==Structure== | ==Structure== | ||
| - | + | The insulin receptor is a [https://en.wikipedia.org/wiki/Transmembrane_protein] | |
===Conformational Changes=== | ===Conformational Changes=== | ||
| Line 17: | Line 17: | ||
It was found that at least three insulin molecules would have to bound to the receptor for the receptor to take on its active “T-state” conformation <ref name="Uchikawa" />. The difference between have the fully bound state with four insulins and the three insulin bound state is minimal compared to the difference between two and three insulins bound <ref name="Uchikawa" />. | It was found that at least three insulin molecules would have to bound to the receptor for the receptor to take on its active “T-state” conformation <ref name="Uchikawa" />. The difference between have the fully bound state with four insulins and the three insulin bound state is minimal compared to the difference between two and three insulins bound <ref name="Uchikawa" />. | ||
| + | ==Type II Diabetes== | ||
== References == | == References == | ||
Revision as of 02:41, 23 March 2020
Insulin Receptor
| |||||||||||
