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User:Daniel Mulawa/Sandbox 1
From Proteopedia
| Line 21: | Line 21: | ||
4 subunits | 4 subunits | ||
Nicastran (NCT),Anterior pharynx-defective 1 (APH-1), Presenilin (PS1), Presenilin enhancer 2 (PEN-2), and4 phosphatidylcholines stabilize structure (interface between PS1 and PEN-2; APH-1 and PS1; APH-1 and NCT) | Nicastran (NCT),Anterior pharynx-defective 1 (APH-1), Presenilin (PS1), Presenilin enhancer 2 (PEN-2), and4 phosphatidylcholines stabilize structure (interface between PS1 and PEN-2; APH-1 and PS1; APH-1 and NCT) | ||
| - | [[Image:Ribbon structure of whole.png| | + | [[Image:Ribbon structure of whole.png|350 px|right|thumb|Figure 1]] |
[http://http://proteopedia.org/wiki/index.php/5a63 5A63 Article] | [http://http://proteopedia.org/wiki/index.php/5a63 5A63 Article] | ||
===practice=== | ===practice=== | ||
| Line 56: | Line 56: | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
| + | 1.Bai X, Yan C, Guanghui Yang, et al. 2015. An atomic structure of human γ-secretase. Nature. 525:212-217. | ||
| + | 2.Carroll CM, and Li YM. 2016. Physiological and pathological roles of the γ-secretase complex. Brain research bulletin. 126:199-206. | ||
| + | 3.Yang G, Zhou R, Shi Y. 2017. Cryo-EM structures of human γ-secretase. Current Opinion in Structural Biology. 46:55–64. | ||
| + | 4.Yang G, Zhou R, Zhou Q, et al. 2019. Structural basis of Notch recognition by human γ-secretase. Nature. 565: 192-197. | ||
| + | 5.Zhou R, Yang G, Guo X, et al. 2019. Recognition of the amyloid precursor protein by human γ-secretase. Science. 363:1-8. | ||
<references/> | <references/> | ||
Revision as of 20:24, 24 March 2020
Gamma Secretase
=Human Gamma Secretase=
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References
1.Bai X, Yan C, Guanghui Yang, et al. 2015. An atomic structure of human γ-secretase. Nature. 525:212-217. 2.Carroll CM, and Li YM. 2016. Physiological and pathological roles of the γ-secretase complex. Brain research bulletin. 126:199-206. 3.Yang G, Zhou R, Shi Y. 2017. Cryo-EM structures of human γ-secretase. Current Opinion in Structural Biology. 46:55–64. 4.Yang G, Zhou R, Zhou Q, et al. 2019. Structural basis of Notch recognition by human γ-secretase. Nature. 565: 192-197. 5.Zhou R, Yang G, Guo X, et al. 2019. Recognition of the amyloid precursor protein by human γ-secretase. Science. 363:1-8.
Student Contributors
Layla Wisser Daniel Mulawa
