Pyrroline-5-carboxylate dehydrogenase
From Proteopedia
(Difference between revisions)
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*Pyrroline-5-carboxylate dehydrogenase | *Pyrroline-5-carboxylate dehydrogenase | ||
| + | **[[3v9g]], [[4oe5]] – hPCD – human<BR /> | ||
| + | **[[3v9h]], [[3v9i]] – hPCD (mutant) <BR /> | ||
| + | **[[3v9j]], [[4lgz]], [[4e3x]] – mPCD – mouse<BR /> | ||
| + | **[[4oe6]] – yPCD – yeast<br /> | ||
**[[1uzb]] - TtPCD –''Termus thermophilus''<BR /> | **[[1uzb]] - TtPCD –''Termus thermophilus''<BR /> | ||
**[[4k57]] - TtPCD (mutant)<BR /> | **[[4k57]] - TtPCD (mutant)<BR /> | ||
| - | **[[4oe6]] – yPCD – yeast<br /> | ||
**[[3qan]] – PCD – ''Bacillus halodurans''<BR /> | **[[3qan]] – PCD – ''Bacillus halodurans''<BR /> | ||
**[[3rjl]] - PCD – ''Bacillus licheniformis''<BR /> | **[[3rjl]] - PCD – ''Bacillus licheniformis''<BR /> | ||
| - | **[[3v9g]], [[4oe5]] – hPCD – human<BR /> | ||
| - | **[[3v9h]], [[3v9i]] – hPCD (mutant) <BR /> | ||
| - | **[[3v9j]], [[4lgz]], [[4e3x]] – mPCD – mouse<BR /> | ||
**[[4idm]] – MtPCD – ''Mycobacterium tuberculosis''<br /> | **[[4idm]] – MtPCD – ''Mycobacterium tuberculosis''<br /> | ||
**[[4ids]], [[4jdc]] - MtPCD (mutant)<br /> | **[[4ids]], [[4jdc]] - MtPCD (mutant)<br /> | ||
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*PCD complex with cofactor | *PCD complex with cofactor | ||
| - | **[[ | + | **[[3v9l]] - mPCD + NAD<BR /> |
| - | + | ||
**[[4oe4]] - yPCD + NAD <BR /> | **[[4oe4]] - yPCD + NAD <BR /> | ||
| + | **[[2bhp]], [[2bja]] – TtPCD + NAD<BR /> | ||
**[[2ehq]] - TtPCD + NADP<BR /> | **[[2ehq]] - TtPCD + NADP<BR /> | ||
| - | **[[3v9l]] - mPCD + NAD<BR /> | ||
**[[2bhq]] - TtPCD + glutamate + NAD<BR /> | **[[2bhq]] - TtPCD + glutamate + NAD<BR /> | ||
**[[2bjk]] - TtPCD + citrate + NAD<BR /> | **[[2bjk]] - TtPCD + citrate + NAD<BR /> | ||
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**[[2eiw]], [[2ej6]], [[2j40]] - TtPCD + proline + NAD<BR /> | **[[2eiw]], [[2ej6]], [[2j40]] - TtPCD + proline + NAD<BR /> | ||
**[[2j5n]] - TtPCD + glycine + NAD<BR /> | **[[2j5n]] - TtPCD + glycine + NAD<BR /> | ||
| + | **[[4ihi]] - MtPCD + NAD<BR /> | ||
**[[4ns3]] - MtPCD (mutant) + cobalamin + NAD<br /> | **[[4ns3]] - MtPCD (mutant) + cobalamin + NAD<br /> | ||
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**[[4lh2]] - mPCD + succinate<br /> | **[[4lh2]] - mPCD + succinate<br /> | ||
**[[4lh3]] - mPCD + glutarate<br /> | **[[4lh3]] - mPCD + glutarate<br /> | ||
| - | **[[3v9k | + | **[[3v9k]] - mPCD + proline |
**[[4lem]] - MtPCD (mutant) + cobalamin<br /> | **[[4lem]] - MtPCD (mutant) + cobalamin<br /> | ||
**[[2iy6]] - TtPCD + citrate<br /> | **[[2iy6]] - TtPCD + citrate<br /> | ||
Revision as of 07:26, 13 October 2020
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3D structures of pyrroline-5-carboxylate dehydrogenase
Updated on 13-October-2020
References
- ↑ Deuschle K, Funck D, Forlani G, Stransky H, Biehl A, Leister D, van der Graaff E, Kunze R, Frommer WB. The role of [Delta]1-pyrroline-5-carboxylate dehydrogenase in proline degradation. Plant Cell. 2004 Dec;16(12):3413-25. Epub 2004 Nov 17. PMID:15548746 doi:http://dx.doi.org/10.1105/tpc.104.023622
- ↑ Geraghty MT, Vaughn D, Nicholson AJ, Lin WW, Jimenez-Sanchez G, Obie C, Flynn MP, Valle D, Hu CA. Mutations in the Delta1-pyrroline 5-carboxylate dehydrogenase gene cause type II hyperprolinemia. Hum Mol Genet. 1998 Sep;7(9):1411-5. PMID:9700195
- ↑ Pemberton TA, Tanner JJ. Structural basis of substrate selectivity of Delta-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): Semialdehyde chain length. Arch Biochem Biophys. 2013 Aug 6. pii: S0003-9861(13)00231-2. doi:, 10.1016/j.abb.2013.07.024. PMID:23928095 doi:10.1016/j.abb.2013.07.024
