Rhomboid protease

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*Rhomboid protease
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*Rhomboid protease GlpG
**[[2ic8]], [[2irv]], [[2nrf]], [[2o7l]], [[3b45]], [[2xov]], [[4njn]], [[4njp]] – EcGlpG core region – ''Escherichia coli '' <BR />
**[[2ic8]], [[2irv]], [[2nrf]], [[2o7l]], [[3b45]], [[2xov]], [[4njn]], [[4njp]] – EcGlpG core region – ''Escherichia coli '' <BR />
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**[[2gqc]] – RP N terminal – NMR – ''Pseudomonas aeruginosa''<br />
**[[2gqc]] – RP N terminal – NMR – ''Pseudomonas aeruginosa''<br />
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*Rhomboid protease complex with inhibitor
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*Rhomboid protease GlpG complex with inhibitor
**[[2xow]], [[3zeb]] – EcGlpG core region + isocoumarin inhibitor <BR />
**[[2xow]], [[3zeb]] – EcGlpG core region + isocoumarin inhibitor <BR />

Revision as of 10:02, 22 October 2020

Structure of rhomboid protease complex with inhibitor isocoumarin and nonyglucoside detergent molecules (PDB entry 2xow)

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3D Structures of rhomboid protease

Updated on 22-October-2020

References

  1. Freeman M. Rhomboid proteases and their biological functions. Annu Rev Genet. 2008;42:191-210. doi: 10.1146/annurev.genet.42.110807.091628. PMID:18605900 doi:http://dx.doi.org/10.1146/annurev.genet.42.110807.091628
  2. Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M. The structural basis for catalysis and substrate specificity of a rhomboid protease. EMBO J. 2010 Oct 1. PMID:20890268 doi:10.1038/emboj.2010.243

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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