Adenosine A2A receptor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 16: Line 16:
Like other G proteins, <scene name='54/540144/Cv/5'>A2AR has 7 transmembrane helices</scene>.
Like other G proteins, <scene name='54/540144/Cv/5'>A2AR has 7 transmembrane helices</scene>.
-
*<scene name='54/540144/Cv/8'>A2AR posses a ligand-binding cavity</scene>.
+
*<scene name='54/540144/Cv/8'>A2AR has a ligand-binding cavity</scene>.
*<scene name='54/540144/Cv/7'>Adenosine binding site</scene>.
*<scene name='54/540144/Cv/7'>Adenosine binding site</scene>.

Revision as of 07:13, 28 February 2021

Human A2AR (mutant) complex with adenosine 2ydo

Drag the structure with the mouse to rotate


References

  1. Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, Tate CG. Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation. Nature. 2011 May 18. PMID:21593763 doi:10.1038/nature10136
  2. Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF. Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. J Neurosci. 2011 Jul 6;31(27):10067-75. doi: 10.1523/JNEUROSCI.6730-10.2011. PMID:21734299 doi:http://dx.doi.org/10.1523/JNEUROSCI.6730-10.2011

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Nina Clavio, Joel L. Sussman

Personal tools